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Combinations of cer...
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Arena, Mattia PiaUniversity of Foggia
(author)
Combinations of cereal β-glucans and probiotics can enhance the anti-inflammatory activity on host cells by a synergistic effect
- Article/chapterEnglish2016
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LIBRIS-ID:oai:lup.lub.lu.se:3445335c-020d-4224-8714-51a188f2b38c
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https://lup.lub.lu.se/record/3445335c-020d-4224-8714-51a188f2b38cURI
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https://doi.org/10.1016/j.jff.2016.02.015DOI
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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The influence of oat and barley β-glucans on some features of diverse probiotic strains was investigated. Neither barley nor oat β-glucans supported the growth of any of the investigated strains when used as the sole carbon source in fermentation media. No protective effect by β-glucans was observed on bacterial survival to in vitro simulation of the human digestive tract. Moreover, the presence of β-glucans did not enhance the ability of probiotic bacteria to adhere on human intestinal cells. The immunomodulatory activities of probiotics, β-glucans, and their combinations were studied and compared in vitro by transcriptional analysis of immune-related genes on LPS-stimulated THP-1 macrophages. Immune modulating properties were evidenced. In particular, mixtures of probiotic microorganisms and barley β-glucans exhibited synergistic effects in modulating the transcriptional level of several immune-related genes, leading to an overall enhanced anti-inflammatory effect. Together, these findings suggest a promising application of probiotic bacteria and β-glucans in the preparation of dietary mixtures presenting health-promoting features such as immunomodulatory properties.
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Russo, PasqualePromis Biotech srl
(author)
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Capozzi, VittorioUniversity of Foggia
(author)
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Rascón, AnaLund University,Lunds universitet,Centrum för preventiv livsmedelsforskning,Universitetets särskilda verksamheter,Food for Health Science Centre,University Specialised Centres,Aventure AB(Swepub:lu)biot-aro
(author)
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Felis, Giovanna E.University of Verona
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Spano, GiuseppeUniversity of Foggia
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Fiocco, DanielaUniversity of Foggia
(author)
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University of FoggiaPromis Biotech srl
(creator_code:org_t)
Related titles
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In:Journal of Functional Foods: Elsevier BV23, s. 12-231756-4646
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