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The relationship be...
The relationship between the metabolic syndrome and arterial wall thickness : A mosaic still to be interpreted
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- Scuteri, Angelo (author)
- University of Rome Tor Vergata
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- Franco, Oscar H. (author)
- Erasmus University Medical Center
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- Völzke, Henry (author)
- University of Greifswald
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- Shin, Min Ho (author)
- Chonnam National University
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- Kweon, Sun Seog (author)
- Chonnam National University
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- Rietzschel, Ernst (author)
- Ghent University Hospital,Ghent University
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- Ryliškytė, Ligita (author)
- Vilnius University Hospital
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- Strazhesko, Irina (author)
- Federal State Institution National Research Center for Preventive Medicine, Russia
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- Chen, Chen Huan (author)
- National Yang-Ming University Taiwan
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- Lakatta, Edward G. (author)
- National Institute on Aging, United States
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- Nilsson, Peter M. (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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(creator_code:org_t)
- Elsevier BV, 2016
- 2016
- English 6 s.
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In: Atherosclerosis. - : Elsevier BV. - 0021-9150. ; 255, s. 11-16
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
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- Background and aims We aimed to identify clusters of metabolic syndrome (MetS) components, risky for extremely high intima-media thickness. Methods We studied 41,513 volunteers (men and women) from eleven cohorts worldwide, participating in the MARE (Metabolic syndrome and Artery REsearch) Consortium. Results Specific clusters of MetS components - high triglycerides-high blood pressure-abdominal obesity (TBW), low HDL cholesterol-high blood pressure-abdominal obesity (HBW), high glucose-high blood pressure-abdominal obesity (GBW) - were accompanied by a 50–90% significantly greater likelihood of presenting extremely high intima-media thickness (via ultrasound of carotid artery, CCA IMT), after controlling for age, sex, smoking, non-HDL cholesterol, and presence of diabetes mellitus. This likelihood is comparable to the effect of being 7–8 years older or of being a cigarette smoker or of having non-HDL cholesterol 50 mg/dl higher. Conclusions The consistent association of specific clusters of MetS components with extremely thick (older) large artery cross-culturally suggests that identification of those clusters in clinical practice will facilitate a personalized health care and a better – i.e. more healthy and cost-effective - prevention of major cardiovascular (CV) events.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Arterial ageing
- Arteries
- Carotid intima-media thickness
- Metabolic syndrome
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Scuteri, Angelo
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Franco, Oscar H.
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Völzke, Henry
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Shin, Min Ho
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Kweon, Sun Seog
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Rietzschel, Erns ...
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show more...
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Ryliškytė, Ligit ...
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Strazhesko, Irin ...
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Chen, Chen Huan
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Lakatta, Edward ...
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Nilsson, Peter M ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Atherosclerosis
- By the university
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Lund University