Search: onr:"swepub:oai:lup.lub.lu.se:38be3c71-e9dd-4546-91b4-1e37154012be" >
Functional imaging ...
-
Linguiti, SophiaUniversity of Pennsylvania
(author)
Functional imaging studies of acute administration of classic psychedelics, ketamine, and MDMA : Methodological limitations and convergent results
- Article/chapterEnglish2023
Publisher, publication year, extent ...
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:38be3c71-e9dd-4546-91b4-1e37154012be
-
https://lup.lub.lu.se/record/38be3c71-e9dd-4546-91b4-1e37154012beURI
-
https://doi.org/10.1016/j.neubiorev.2023.105421DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:for swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
Functional magnetic resonance imaging (fMRI) is increasingly used to non-invasively study the acute impact of psychedelics on the human brain. While fMRI is a promising tool for measuring brain function in response to psychedelics, it also has known methodological challenges. We conducted a systematic review of fMRI studies examining acute responses to experimentally administered psychedelics in order to identify convergent findings and characterize heterogeneity in the literature. We reviewed 91 full-text papers; these studies were notable for substantial heterogeneity in design, task, dosage, drug timing, and statistical approach. Data recycling was common, with 51 unique samples across 91 studies. Fifty-seven studies (54%) did not meet contemporary standards for Type I error correction or control of motion artifact. Psilocybin and LSD were consistently reported to moderate the connectivity architecture of the sensorimotor-association cortical axis. Studies also consistently reported that ketamine administration increased activation in the dorsomedial prefrontal cortex. Moving forward, use of best practices such as pre-registration, standardized image processing and statistical testing, and data sharing will be important in this rapidly developing field.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Vogel, Jacob W.Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Clinical Memory Research,Lund University Research Groups,LU Profile Area: Proactive Ageing,Lund University Profile areas,University of Pennsylvania(Swepub:lu)ja8870vo
(author)
-
Sydnor, Valerie J.University of Pennsylvania
(author)
-
Pines, AdamUniversity of Pennsylvania,Stanford University
(author)
-
Wellman, NickUniversity of Pennsylvania
(author)
-
Basbaum, AllanUniversity of California, San Francisco
(author)
-
Eickhoff, Claudia R.Jülich Research Centre
(author)
-
Eickhoff, Simon B.Jülich Research Centre
(author)
-
Edwards, Robert R.Harvard Medical School
(author)
-
Larsen, BartUniversity of Pennsylvania
(author)
-
McKinstry-Wu, AndrewUniversity of Pennsylvania
(author)
-
Scott, J. CobbVeterans Health Administration,University of Pennsylvania
(author)
-
Roalf, David R.University of Pennsylvania
(author)
-
Sharma, VaishnaviUniversity of Pennsylvania
(author)
-
Strain, Eric C.Johns Hopkins University School of Medicine
(author)
-
Corder, GregoryUniversity of Pennsylvania
(author)
-
Dworkin, Robert H.University of Rochester School of Medicine and Dentistry
(author)
-
Satterthwaite, Theodore D.University of Pennsylvania
(author)
-
University of PennsylvaniaKlinisk minnesforskning
(creator_code:org_t)
Related titles
-
In:Neuroscience and Biobehavioral Reviews1540149-7634
Internet link
Find in a library
To the university's database
- By the author/editor
-
Linguiti, Sophia
-
Vogel, Jacob W.
-
Sydnor, Valerie ...
-
Pines, Adam
-
Wellman, Nick
-
Basbaum, Allan
-
show more...
-
Eickhoff, Claudi ...
-
Eickhoff, Simon ...
-
Edwards, Robert ...
-
Larsen, Bart
-
McKinstry-Wu, An ...
-
Scott, J. Cobb
-
Roalf, David R.
-
Sharma, Vaishnav ...
-
Strain, Eric C.
-
Corder, Gregory
-
Dworkin, Robert ...
-
Satterthwaite, T ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Medical Biotechn ...
-
and Biomedical Labor ...
- Articles in the publication
-
Neuroscience and ...
- By the university
-
Lund University