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Abnormal fetal aortic velocity waveform and minor neurological dysfunction at 7 years of age

Ley, D (author)
Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neonatalogi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Neonatology,Lund University Research Groups,Skåne University Hospital
Laurin, J (author)
Skåne University Hospital
Bjerre, I (author)
Skåne University Hospital
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Marsal, K (author)
Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tornbladinstitutet,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Tornblad Institute,Lund University Research Groups,Skåne University Hospital
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 (creator_code:org_t)
2003-01-22
1996
English.
In: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. - : Wiley. - 0960-7692. ; 8:3, s. 9-152
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Measurements of fetal aortic blood flow velocity and fetal growth were performed in 178 pregnancies. In 87 cases, the estimated fetal weight was > or = 2 SD below the gestational age-related mean of the population. Three fetuses died in utero. In 149 children (85%), a neurological examination was performed at 7 years of age with special emphasis on minor neurological dysfunction. The frequency of the more severe form of minor neurological dysfunction, MND-2, was higher in the group with blood flow class (BFC) III (absent or reversed end-diastolic flow velocity (8/21) than in the group with BFC 0 (normal velocity waveform) (14/105). Logistic regression analysis revealed that abnormal blood flow class, both independently and in combination with other factors, was the most significant predictor of MND-2. The association found between abnormal fetal aortic velocity waveforms and adverse outcome in terms of minor neurological dysfunction suggests that hemodynamic evaluation of the fetus has a predictive value regarding postnatal neurological development.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Keyword

Analysis of Variance
Aorta, Thoracic/diagnostic imaging
Blood Flow Velocity
Child
Child Development
Female
Fetal Growth Retardation/complications
Fetal Heart/physiopathology
Hemodynamics/physiology
Humans
Infant, Newborn
Infant, Small for Gestational Age
Logistic Models
Longitudinal Studies
Nervous System Diseases/diagnosis
Predictive Value of Tests
Pregnancy
Prospective Studies
Risk Factors
Ultrasonography, Prenatal

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By the author/editor
Ley, D
Laurin, J
Bjerre, I
Marsal, K
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Pediatrics
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Ultrasound in ob ...
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Lund University

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