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Depression Severity...
Depression Severity, but Not Cognitive Impairment or Frailty, is Associated with Disability in Late-Life Depression
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- Morin, Ruth T. (author)
- Veterans Health Administration
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- Insel, Philip (author)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Veterans Health Administration
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- Bickford, David (author)
- Medical College of Wisconsin
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- Nelson, Craig (author)
- University of California, San Francisco
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- Mackin, R. Scott (author)
- University of California, San Francisco,Veterans Health Administration
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(creator_code:org_t)
- 2019-12-21
- 2020
- English 9 s.
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In: Clinical Gerontologist. - : Informa UK Limited. - 0731-7115 .- 1545-2301. ; 43:4, s. 411-419
- Related links:
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http://dx.doi.org/10...
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Abstract
Subject headings
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- Objectives: Assess the relationship of cognitive impairment to disability, accounting for depression severity and frailty, among older adults with late-life depression (LLD). Methods: Data were analyzed from 78 community-dwelling older adults with LLD and without dementia (age M = 71.9; SD = 6.1). Cognitive functioning was assessed using a comprehensive neuropsychological battery. Depression severity was measured using the 17-item Hamilton Depression Rating Scale (HDRS; cutoff ≥15). Frailty was assessed using several motor tests. The World Health Organization Disability Assessment Schedule (WHO-DAS) measured disability status. A linear regression analysis was performed to identify relationships of cognition, frailty and depression severity with disability. Results: The average number of impaired cognitive tests was 2.0 (SD = 1.9), with 28.2% of participants showing no impaired scores. On average participants reported depression severity of 17.3 (SD = 3.6), and disability total score of 15.1 (SD = 6.9). The regression model accounted for 25.1% of the variance in disability, with only depression severity significantly predicting disability status. Burden of cognitive impairment and frailty were not predictive of disability in this sample. Conclusions: In this sample, only depression severity was associated with increased disability. Clinical Implications: These findings have implications for intervention in LLD, as depression severity may represent a more modifiable risk factor for disability.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)
Keyword
- cognitive impairment
- disability
- frailty
- Late life depression
Publication and Content Type
- art (subject category)
- ref (subject category)
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