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Bubble coalescence ...
Bubble coalescence in breathing DNA: Two vicious walkers in opposite potentials
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Novotny, T. (author)
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- Pedersen, Jonas (author)
- Lund University,Lunds universitet,Matematisk fysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Mathematical Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH
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- Ambjörnsson, T. (author)
- Massachusetts Institute of Technology,Nordic Institute for Theoretical Atomic Physics (NORDITA), Copenhagen
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Hansen, M. S. (author)
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Metzler, R. (author)
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(creator_code:org_t)
- 2007-01-25
- 2007
- English.
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In: Europhysics Letters. - : IOP Publishing. - 0295-5075 .- 1286-4854. ; 77:4
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Abstract
Subject headings
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- We investigate the coalescence of two DNA bubbles initially located at weak segments and separated by a more stable barrier region in a designed construct of double-stranded DNA. The characteristic time for bubble coalescence and the corresponding distribution are derived, as well as the distribution of coalescence positions along the barrier. Below the melting temperature, we find a Kramers-type barrier crossing behaviour, while at high temperatures, the bubble corners perform drift-diffusion towards coalescence. The results are obtained by mapping the bubble dynamics on the problem of two vicious walkers in opposite potentials.
Subject headings
- NATURVETENSKAP -- Biologi -- Biofysik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biophysics (hsv//eng)
- NATURVETENSKAP -- Fysik -- Annan fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Other Physics Topics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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