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The exposome and immune health in times of the covid-19 pandemic

Morales, Javier S. (author)
University of Cádiz,Puerta del Mar University Hospital
Valenzuela, Pedro L. (author)
European University of Madrid,12 de Octubre University Hospital
Castillo-García, Adrián (author)
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Butragueño, Javier (author)
Technical University of Madrid
Jiménez-Pavón, David (author)
University of Cádiz,Puerta del Mar University Hospital
Carrera-Bastos, Pedro (author)
Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups,European University of Madrid
Lucia, Alejandro (author)
European University of Madrid,12 de Octubre University Hospital
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 (creator_code:org_t)
2021-12-22
2022
English.
In: Nutrients. - : MDPI AG. - 2072-6643. ; 14:1
  • Research review (peer-reviewed)
Abstract Subject headings
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  • Growing evidence supports the importance of lifestyle and environmental exposures— collectively referred to as the ‘exposome’—for ensuring immune health. In this narrative review, we summarize and discuss the effects of the different exposome components (physical activity, body weight management, diet, sun exposure, stress, sleep and circadian rhythms, pollution, smoking, and gut microbiome) on immune function and inflammation, particularly in the context of the current coronavirus disease 2019 (COVID-19) pandemic. We highlight the potential role of ‘exposome improvements’ in the prevention—or amelioration, once established—of this disease as well as their effect on the response to vaccination. In light of the existing evidence, the promotion of a healthy exposome should be a cornerstone in the prevention and management of the COVID-19 pandemic and other eventual pandemics.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Keyword

COVID-19
Environmental exposure
Healthy lifestyle
Infectious diseases
Vaccines

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