Search: onr:"swepub:oai:lup.lub.lu.se:4665e44d-6196-47f9-a47a-7cd7820ab69e" > Creation of an Open...
Fältnamn | Indikatorer | Metadata |
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000 | 05205naa a2200889 4500 | |
001 | oai:lup.lub.lu.se:4665e44d-6196-47f9-a47a-7cd7820ab69e | |
003 | SwePub | |
008 | 160401s2012 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/31471362 URI |
024 | 7 | a https://doi.org/10.1371/journal.pone.00430992 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Wray, Selina4 aut |
245 | 1 0 | a Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research |
264 | c 2012-08-27 | |
264 | 1 | b Public Library of Science (PLoS),c 2012 |
338 | a electronic2 rdacarrier | |
520 | a Our understanding of the molecular mechanisms of many neurological disorders has been greatly enhanced by the discovery of mutations in genes linked to familial forms of these diseases. These have facilitated the generation of cell and animal models that can be used to understand the underlying molecular pathology. Recently, there has been a surge of interest in the use of patient-derived cells, due to the development of induced pluripotent stem cells and their subsequent differentiation into neurons and glia. Access to patient cell lines carrying the relevant mutations is a limiting factor for many centres wishing to pursue this research. We have therefore generated an open-access collection of fibroblast lines from patients carrying mutations linked to neurological disease. These cell lines have been deposited in the National Institute for Neurological Disorders and Stroke (NINDS) Repository at the Coriell Institute for Medical Research and can be requested by any research group for use in in vitro disease modelling. There are currently 71 mutation-defined cell lines available for request from a wide range of neurological disorders and this collection will be continually expanded. This represents a significant resource that will advance the use of patient cells as disease models by the scientific community. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Geriatrik0 (SwePub)302222 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Geriatrics0 (SwePub)302222 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
700 | 1 | a Self, Matthew4 aut |
700 | 1 | a Lewis, Patrick A.4 aut |
700 | 1 | a Taanman, Jan-Willem4 aut |
700 | 1 | a Ryan, Natalie S.4 aut |
700 | 1 | a Mahoney, Colin J.4 aut |
700 | 1 | a Liang, Yuying4 aut |
700 | 1 | a Devine, Michael J.4 aut |
700 | 1 | a Sheerin, Una-Marie4 aut |
700 | 1 | a Houlden, Henry4 aut |
700 | 1 | a Morris, Huw R.4 aut |
700 | 1 | a Healy, Daniel4 aut |
700 | 1 | a Marti-Masso, Jose-Felix4 aut |
700 | 1 | a Preza, Elisavet4 aut |
700 | 1 | a Barker, Suzanne4 aut |
700 | 1 | a Sutherland, Margaret4 aut |
700 | 1 | a Corriveau, Roderick A.4 aut |
700 | 1 | a D'Andrea, Michael4 aut |
700 | 1 | a Schapira, Anthony H. V.4 aut |
700 | 1 | a Uitti, Ryan J.4 aut |
700 | 1 | a Guttman, Mark4 aut |
700 | 1 | a Opala, Grzegorz4 aut |
700 | 1 | a Jasinska-Myga, Barbara4 aut |
700 | 1 | a Puschmann, Andreasu Lund University,Lunds universitet,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-aps |
700 | 1 | a Nilsson, Christeru Lund University,Lunds universitet,Psykiatri, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Psychiatry (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)neur-cni |
700 | 1 | a Espay, Alberto J.4 aut |
700 | 1 | a Slawek, Jaroslaw4 aut |
700 | 1 | a Gutmann, Ludwig4 aut |
700 | 1 | a Boeve, Bradley F.4 aut |
700 | 1 | a Boylan, Kevin4 aut |
700 | 1 | a Stoessl, A. Jon4 aut |
700 | 1 | a Ross, Owen A.4 aut |
700 | 1 | a Maragakis, Nicholas J.4 aut |
700 | 1 | a Van Gerpen, Jay4 aut |
700 | 1 | a Gerstenhaber, Melissa4 aut |
700 | 1 | a Gwinn, Katrina4 aut |
700 | 1 | a Dawson, Ted M.4 aut |
700 | 1 | a Isacson, Ole4 aut |
700 | 1 | a Marder, Karen S.4 aut |
700 | 1 | a Clark, Lorraine N.4 aut |
700 | 1 | a Przedborski, Serge E.4 aut |
700 | 1 | a Finkbeiner, Steven4 aut |
700 | 1 | a Rothstein, Jeffrey D.4 aut |
700 | 1 | a Wszolek, Zbigniew K.4 aut |
700 | 1 | a Rossor, Martin N.4 aut |
700 | 1 | a Hardy, John4 aut |
710 | 2 | a Sektion IVb Institutionen för kliniska vetenskaper, Lund4 org |
773 | 0 | t PLoS ONEd : Public Library of Science (PLoS)g 7:8q 7:8x 1932-6203 |
856 | 4 | u https://portal.research.lu.se/files/3483059/3217131.pdfx primaryx freey FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1371/journal.pone.0043099x freey FULLTEXT |
856 | 4 | u https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043099&type=printable |
856 | 4 8 | u https://lup.lub.lu.se/record/3147136 |
856 | 4 8 | u https://doi.org/10.1371/journal.pone.0043099 |
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