Search: onr:"swepub:oai:lup.lub.lu.se:494de5fe-0a96-4e95-9cb3-0aa5d1ff1f93" > Lifestyle factors a...
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000 | 09450naa a2201105 4500 | |
001 | oai:lup.lub.lu.se:494de5fe-0a96-4e95-9cb3-0aa5d1ff1f93 | |
003 | SwePub | |
008 | 200127s2020 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-168685 | |
024 | 7 | a https://lup.lub.lu.se/record/494de5fe-0a96-4e95-9cb3-0aa5d1ff1f932 URI |
024 | 7 | a https://doi.org/10.1186/s12916-019-1474-72 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1686852 URI |
040 | a (SwePub)lud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Freisling, Heinzu International Agency for Research on Cancer, World Health Organization4 aut |
245 | 1 0 | a Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases : a multinational cohort study |
264 | c 2020-01-10 | |
264 | 1 | b Springer Science and Business Media LLC,c 2020 |
520 | a BACKGROUND: Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely investigated. The aim of this study was to investigate associations between five lifestyle factors and incident multimorbidity of cancer and cardiometabolic diseases. METHODS: In this prospective cohort study, 291,778 participants (64% women) from seven European countries, mostly aged 43 to 58 years and free of cancer, cardiovascular disease (CVD), and type 2 diabetes (T2D) at recruitment, were included. Incident multimorbidity of cancer and cardiometabolic diseases was defined as developing subsequently two diseases including first cancer at any site, CVD, and T2D in an individual. Multi-state modelling based on Cox regression was used to compute hazard ratios (HR) and 95% confidence intervals (95% CI) of developing cancer, CVD, or T2D, and subsequent transitions to multimorbidity, in relation to body mass index (BMI), smoking status, alcohol intake, physical activity, adherence to the Mediterranean diet, and their combination as a healthy lifestyle index (HLI) score. Cumulative incidence functions (CIFs) were estimated to compute 10-year absolute risks for transitions from healthy to cancer at any site, CVD (both fatal and non-fatal), or T2D, and to subsequent multimorbidity after each of the three NCDs. RESULTS: During a median follow-up of 11 years, 1910 men and 1334 women developed multimorbidity of cancer and cardiometabolic diseases. A higher HLI, reflecting healthy lifestyles, was strongly inversely associated with multimorbidity, with hazard ratios per 3-unit increment of 0.75 (95% CI, 0.71 to 0.81), 0.84 (0.79 to 0.90), and 0.82 (0.77 to 0.88) after cancer, CVD, and T2D, respectively. After T2D, the 10-year absolute risks of multimorbidity were 40% and 25% for men and women, respectively, with unhealthy lifestyle, and 30% and 18% for men and women with healthy lifestyles. CONCLUSION: Pre-diagnostic healthy lifestyle behaviours were strongly inversely associated with the risk of cancer and cardiometabolic diseases, and with the prognosis of these diseases by reducing risk of multimorbidity. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
653 | a Cancer | |
653 | a Cancer and cardiometabolic multimorbidity | |
653 | a Cardiovascular disease | |
653 | a Diabetes | |
653 | a Healthy lifestyle | |
653 | a Obesity | |
653 | a Prevention | |
653 | a Cancer | |
700 | 1 | a Viallon, Vivianu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Lennon, Hannahu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Bagnardi, Vincenzou University of Milano-Bicocca4 aut |
700 | 1 | a Ricci, Cristianu North-West University4 aut |
700 | 1 | a Butterworth, Adam S.u University of Cambridge4 aut |
700 | 1 | a Sweeting, Michaelu University of Cambridge4 aut |
700 | 1 | a Muller, Davidu Imperial College London4 aut |
700 | 1 | a Romieu, Isabelleu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Bazelle, Paulineu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Kvaskoff, Marinau University of Paris-Saclay,Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Arveux, Patricku Centre for Research in Epidemiology and Population Health (CESP),Breast and Gynaecologic Cancer Registry of Côte d'Or,Centre Georges-François Leclerc4 aut |
700 | 1 | a Severi, Gianlucau Centre for Research in Epidemiology and Population Health (CESP),Human Genetics Foundation (HuGeF),University of Paris-Saclay4 aut |
700 | 1 | a Bamia, Christinau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Kühn, Tilmanu German Cancer Research Centre4 aut |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre4 aut |
700 | 1 | a Bergmann, Manuelau German Institute of Human Nutrition4 aut |
700 | 1 | a Boeing, Heineru German Institute of Human Nutrition4 aut |
700 | 1 | a Tjønneland, Anneu Danish Cancer Society4 aut |
700 | 1 | a Olsen, Anjau Danish Cancer Society4 aut |
700 | 1 | a Overvad, Kimu Aarhus University4 aut |
700 | 1 | a Dahm, Christina C.u Aarhus University4 aut |
700 | 1 | a Menéndez, Virginiau Public Health Directorate4 aut |
700 | 1 | a Agudo, Antoniou Bellvitge University Hospital-IDIBELL,Bellvitge Biomedical Research Institute,L'Hospitalet de Llobregat, Barcelona,University of Oxford4 aut |
700 | 1 | a Sánchez, Maria Joseu University of Granada,CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Amiano, Pilaru Biodonostia Health Research Institute,CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Santiuste, Carmenu Murcia Regional Health Council4 aut |
700 | 1 | a Gurrea, Aurelio Barricarteu CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Tong, Tammy Y.N.u University of Oxford4 aut |
700 | 1 | a Schmidt, Julie A.u University of Oxford4 aut |
700 | 1 | a Tzoulaki, Ioannau Imperial College London,University of Ioannina4 aut |
700 | 1 | a Tsilidis, Konstantinos K.u University of Ioannina,Imperial College London4 aut |
700 | 1 | a Ward, Heatheru Imperial College London4 aut |
700 | 1 | a Palli, Domenicou Institute for Cancer Research, Prevention and Clinical Network (ISPRO)4 aut |
700 | 1 | a Agnoli, Claudiau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Tumino, Rosariou Civic and M.P Arezzo Hospital4 aut |
700 | 1 | a Ricceri, Fulviou Citta' della Salute e della Scienza Hospital-University of Turin4 aut |
700 | 1 | a Panico, Salvatoreu University of Naples Federico II4 aut |
700 | 1 | a Picavet, H. Susan J.u National Institute for Public Health and the Environment (RIVM)4 aut |
700 | 1 | a Bakker, Marijeu University Medical Center Utrecht4 aut |
700 | 1 | a Monninkhof, Evelynu University Medical Center Utrecht4 aut |
700 | 1 | a Nilsson, Peteru Umeå universitet,Umeå University,Näringsforskning4 aut |
700 | 1 | a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)smi-jma |
700 | 1 | a Rolandsson, Olovu Umeå universitet,Umeå University,Allmänmedicin4 aut0 (Swepub:umu)olro0005 |
700 | 1 | a Thysell, Elinu Umeå University4 aut |
700 | 1 | a Weiderpass, Elisabeteu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Jenab, Mazdau International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Riboli, Eliou Imperial College London4 aut |
700 | 1 | a Vineis, Paolou Imperial College London4 aut |
700 | 1 | a Danesh, Johnu University of Cambridge4 aut |
700 | 1 | a Wareham, Nick Ju University of Cambridge4 aut |
700 | 1 | a Gunter, Marc J.u International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization4 aut |
710 | 2 | a International Agency for Research on Cancer, World Health Organizationb University of Milano-Bicocca4 org |
773 | 0 | t BMC Medicined : Springer Science and Business Media LLCg 18:1q 18:1x 1741-7015 |
856 | 4 | u http://dx.doi.org/10.1186/s12916-019-1474-7x freey FULLTEXT |
856 | 4 | u https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-019-1474-7 |
856 | 4 | u https://doi.org/10.1186/s12916-019-1474-7y Fulltext |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1412214/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://lup.lub.lu.se/record/494de5fe-0a96-4e95-9cb3-0aa5d1ff1f93 |
856 | 4 8 | u https://doi.org/10.1186/s12916-019-1474-7 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-168685 |
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