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- Uddman, RolfLund University,Lunds universitet,Klinisk och experimentell allergiforskning,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Clinical and Experimental Allergy Research,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups (author)
Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2.
- Article/chapterEnglish2002
Publisher, publication year, extent ...
- 2016-11-17
- SAGE Publications,2002
- electronicrdacarrier
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:4acbb892-c1b7-4a53-b6f0-75a042f734ae
- https://lup.lub.lu.se/record/115413URI
- https://doi.org/10.1046/j.1468-2982.2002.00324.xDOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- In migraine and other primary headaches there is a strong vascular component. Besides the trigeminovascular components some of the associated symptoms point to the involvement of brain stem regions. The central limb of the trigeminal vascular pathway is its projection to the trigeminal nucleus caudalis (TNC) and to the C1-C2 levels of the spinal cord. The aim of the present study was to demonstrate the occurrence of some neurotransmitters in these regions in man. In both the TNC and in the Rexed's laminae I and II of the dorsal horns at the C1 and C2 levels there were numerous substance P immunoreactive fibres. Fibres containing calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating peptide (PACAP) were moderately dense in number. Fibres containing vasoactive intestinal peptide (VIP) or nitric oxide synthase (NOS) were not seen in the TNC or at the C1 and C2 levels of the spinal cord.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Cell- och molekylärbiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Cell and Molecular Biology hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Annan klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Other Clinical Medicine hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Oto-rhino-laryngologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Otorhinolaryngology hsv//eng
- Vasoactive Intestinal Peptide: metabolism
- Adult
- Aged
- Calcitonin Gene-Related Peptide: metabolism
- Cervical Vertebrae
- Non-U.S. Gov't
- Trigeminal Caudal Nucleus: metabolism
- Female
- Human
- Immunohistochemistry
- Male
- Middle Age
- Neuropeptides: metabolism
- Spinal Cord: metabolism
- Substance P: metabolism
- Support
Added entries (persons, corporate bodies, meetings, titles ...)
- Tajti, J (author)
- Hou, M (author)
- Sundler, FrankLund University,Lunds universitet,Institutionen för experimentell medicinsk vetenskap,Medicinska fakulteten,Department of Experimental Medical Science,Faculty of Medicine(Swepub:lu)mphy-fsu (author)
- Edvinsson, LarsLund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)med-led (author)
- Klinisk och experimentell allergiforskningLaryngoesofagologi, allergi och livskvalitet (creator_code:org_t)
Related titles
- In:Cephalalgia: SAGE Publications22:2, s. 112-1160333-10241468-2982
Internet link
- https://portal.research.lu.se/files/4507733/623800.pdfFULLTEXT
- http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=11972578&ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSumFULLTEXT
- http://dx.doi.org/10.1046/j.1468-2982.2002.00324.xFULLTEXT
- https://lup.lub.lu.se/search/files/4507733/623800.pdf
- https://lup.lub.lu.se/record/115413
- https://doi.org/10.1046/j.1468-2982.2002.00324.x
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