Search: onr:"swepub:oai:lup.lub.lu.se:4b4b4c33-b612-48be-8d02-8603daec14a5" > A Nordic multicente...
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000 | 04635naa a2200469 4500 | |
001 | oai:lup.lub.lu.se:4b4b4c33-b612-48be-8d02-8603daec14a5 | |
003 | SwePub | |
008 | 170123s2017 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:136637020 | |
024 | 7 | a https://lup.lub.lu.se/record/4b4b4c33-b612-48be-8d02-8603daec14a52 URI |
024 | 7 | a https://doi.org/10.1016/j.jpedsurg.2017.01.0012 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1366370202 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Bjørnland, Kristinu University of Oslo4 aut |
245 | 1 0 | a A Nordic multicenter survey of long-term bowel function after transanal endorectal pull-through in 200 patients with rectosigmoid Hirschsprung disease |
264 | 1 | b Elsevier BV,c 2017 |
520 | a OBJECTIVE: Transanal endorectal pull-through (ERPT) is the most popular technique to treat Hirschsprung disease (HD). Still, there is limited knowledge on long-term bowel function. This cross-sectional, multicenter study assessed long-term bowel function in a large HD population and examined predictors of poor outcome.METHODS: Patients older than four years or their parents filled out a validated questionnaire on bowel function. Clinical details were recorded retrospectively from medical records.RESULTS: 73/200 (37%) patients reported absolutely no impaired bowel function, meaning no constipation, fecal accidents, stoma, appendicostomy or need for enemas. Seven (4%) had a stoma, and 33 (17%) used antegrade or rectal colonic enemas. Most disarrangements of fecal control and constipation were significantly less common in older age group, but abnormal defecation frequency and social problems remained unchanged. Syndromic patients (n=31) experienced frequent fecal accidents (46%) more often than nonsyndromic (14%, P<0.001). Having a syndrome (adjusted OR 5.6, 95% CI 2.1-15, P=0.001) or a complete transanal ERPT (adjusted OR 2.4, 95% CI 1.1-5.7, P=0.038) was significantly associated with poor outcome defined as having a stoma, an appendicostomy, daily fecal accidents or need of regular rectal wash outs.CONCLUSION: A significant number of HD patients experience bowel problems many years after definite surgery. Fecal control was significantly better in older than younger HD patients, but some continued to have considerable bowel problems also as adults. A total transanal ERPT was associated with poorer outcome. Long-term follow-up of HD patients is warranted. Prognosis Study: Level II. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
700 | 1 | a Pakarinen, Mikko Pu University of Helsinki4 aut |
700 | 1 | a Stenstrøm, Pernillau Lund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-pes |
700 | 1 | a Stensrud, Kjetil Ju University of Oslo4 aut |
700 | 1 | a Neuvonen, Mallau University of Helsinki4 aut |
700 | 1 | a Granström, Anna Lu Karolinska Institutet4 aut |
700 | 1 | a Graneli, Christinau Lund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-crg |
700 | 1 | a Pripp, Are Hu Oslo university hospital4 aut |
700 | 1 | a Arnbjörnsson, Einaru Lund University,Lunds universitet,Barnkirurgi,Forskargrupper vid Lunds universitet,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-eas |
700 | 1 | a Emblem, Ragnhildu University of Oslo4 aut |
700 | 1 | a Wester, Tomasu Karolinska Institutet4 aut |
700 | 1 | a Rintala, Risto Ju University of Helsinki4 aut |
710 | 2 | a University of Oslob University of Helsinki4 org |
710 | 2 | a Nordic Pediatric Surgery Study Consortium |
773 | 0 | t Journal of Pediatric Surgeryd : Elsevier BVg 52:9, s. 1458-1464q 52:9<1458-1464x 1531-5037x 0022-3468 |
856 | 4 | u http://dx.doi.org/10.1016/j.jpedsurg.2017.01.001y FULLTEXT |
856 | 4 | u https://helda.helsinki.fi/bitstream/10138/299387/1/1_s2.0_S0022346817300015_main.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/4b4b4c33-b612-48be-8d02-8603daec14a5 |
856 | 4 8 | u https://doi.org/10.1016/j.jpedsurg.2017.01.001 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:136637020 |
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