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Brain injury after cardiac arrest

Perkins, Gavin D. (author)
University of Warwick,University Hospitals Birmingham
Callaway, Clifton W. (author)
University of Pittsburgh
Haywood, Kirstie (author)
University of Warwick
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Neumar, Robert W. (author)
University of Michigan
Lilja, Gisela (author)
Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Centrum för hjärtstopp,Forskargrupper vid Lunds universitet,Brain Injury After Cardiac Arrest,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Center for cardiac arrest,Lund University Research Groups,Skåne University Hospital
Rowland, Matthew J. (author)
University of Oxford
Sawyer, Kelly N. (author)
University of Pittsburgh
Skrifvars, Markus B. (author)
University of Helsinki
Nolan, Jerry P. (author)
University of Warwick,Royal United Hospital, Bath
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 (creator_code:org_t)
2021
2021
English 10 s.
In: The Lancet. - 0140-6736. ; 398:10307, s. 1269-1278
  • Research review (peer-reviewed)
Abstract Subject headings
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  • As more people are surviving cardiac arrest, focus needs to shift towards improving neurological outcomes and quality of life in survivors. Brain injury after resuscitation, a common sequela following cardiac arrest, ranges in severity from mild impairment to devastating brain injury and brainstem death. Effective strategies to minimise brain injury after resuscitation include early intervention with cardiopulmonary resuscitation and defibrillation, restoration of normal physiology, and targeted temperature management. It is important to identify people who might have a poor outcome, to enable informed choices about continuation or withdrawal of life-sustaining treatments. Multimodal prediction guidelines seek to avoid premature withdrawal in those who might survive with a good neurological outcome, or prolonging treatment that might result in survival with severe disability. Approximately one in three admitted to intensive care will survive, many of whom will need intensive, tailored rehabilitation after discharge to have the best outcomes.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

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