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Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease

Donahue, Manus J (author)
Vanderbilt University
Achten, Eric (author)
Ghent University
Cogswell, Petrice M (author)
Vanderbilt University Medical Center
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De Leeuw, Frank-Erik (author)
Radboud University Medical Center
Derdeyn, Colin P (author)
University of Iowa
Dijkhuizen, Rick M (author)
University Medical Center Utrecht
Fan, Audrey P (author)
Stanford University
Ghaznawi, Rashid (author)
University Medical Center Utrecht
Heit, Jeremy J (author)
Stanford University
Ikram, M Arfan (author)
Erasmus University Rotterdam
Jezzard, Peter (author)
Oxford University Hospital
Jordan, Lori C (author)
Vanderbilt University Medical Center
Jouvent, Eric (author)
Hopital Bichat-Claude-Bernard AP-HP
Knutsson, Linda (author)
Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,MR Physics,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Johns Hopkins University School of Medicine
Leigh, Richard (author)
National Institutes of Health, United States
Liebeskind, David S (author)
University of California, Los Angeles
Lin, Weili (author)
University of North Carolina
Okell, Thomas W (author)
Oxford University Hospital
Qureshi, Adnan I (author)
Zeenat Qureshi Stroke Institute
Stagg, Charlotte J (author)
University of Oxford
van Osch, Matthias Jp (author)
Leiden University Medical Centre
van Zijl, Peter Cm (author)
Kennedy Krieger Institute
Watchmaker, Jennifer M (author)
Vanderbilt University Medical Center
Wintermark, Max (author)
Stanford University
Wu, Ona (author)
Harvard Medical School
Zaharchuk, Greg (author)
Stanford University
Zhou, Jinyuan (author)
Kennedy Krieger Institute
Hendrikse, Jeroen (author)
University Medical Center Utrecht
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 (creator_code:org_t)
2018
2018
English.
In: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. - 1559-7016. ; 38:9, s. 1391-1417
  • Research review (peer-reviewed)
Abstract Subject headings
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  • Cerebrovascular disease (CVD) remains a leading cause of death and the leading cause of adult disability in most developed countries. This work summarizes state-of-the-art, and possible future, diagnostic and evaluation approaches in multiple stages of CVD, including (i) visualization of sub-clinical disease processes, (ii) acute stroke theranostics, and (iii) characterization of post-stroke recovery mechanisms. Underlying pathophysiology as it relates to large vessel steno-occlusive disease and the impact of this macrovascular disease on tissue-level viability, hemodynamics (cerebral blood flow, cerebral blood volume, and mean transit time), and metabolism (cerebral metabolic rate of oxygen consumption and pH) are also discussed in the context of emerging neuroimaging protocols with sensitivity to these factors. The overall purpose is to highlight advancements in stroke care and diagnostics and to provide a general overview of emerging research topics that have potential for reducing morbidity in multiple areas of CVD.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)
NATURVETENSKAP  -- Fysik -- Annan fysik (hsv//swe)
NATURAL SCIENCES  -- Physical Sciences -- Other Physics Topics (hsv//eng)

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Journal Article

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