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  • Zanchetti, Alberto (author)

Blood pressure and low-density lipoprotein-cholesterol lowering for prevention of strokes and cognitive decline: a review of available trial evidence.

  • Article/chapterEnglish2014

Publisher, publication year, extent ...

  • 2014

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:5b051e28-2720-40b0-a4ae-39932e49c84c
  • https://lup.lub.lu.se/record/4583898URI
  • https://doi.org/10.1097/HJH.0000000000000253DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:for swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • It is well established by a large number of randomized controlled trials that lowering blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) by drugs are powerful means to reduce stroke incidence, but the optimal BP and LDL-C levels to be achieved are largely uncertain. Concerning BP targets, two hypotheses are being confronted: first, the lower the BP, the better the treatment outcome, and second, the hypothesis that too low BP values are accompanied by a lower benefit and even higher risk. It is also unknown whether BP lowering and LDL-C lowering have additive beneficial effects for the primary and secondary prevention of stroke, and whether these treatments can prevent cognitive decline after stroke.

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  • Liu, Lisheng (author)
  • Mancia, Giuseppe (author)
  • Parati, Gianfranco (author)
  • Grassi, Guido (author)
  • Stramba-Badiale, Marco (author)
  • Silani, Vincenzo (author)
  • Bilo, Grzegorz (author)
  • Corrao, Giovanni (author)
  • Zambon, Antonella (author)
  • Scotti, Lorenza (author)
  • Zhang, Xinhua (author)
  • Wang, HayYan (author)
  • Zhang, Yuqing (author)
  • Zhang, Xuezhong (author)
  • Guan, Ting Rui (author)
  • Berge, Eivind (author)
  • Redon, Josep (author)
  • Narkiewicz, Krzysztof (author)
  • Dominiczak, Anna (author)
  • Nilsson, PeterLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups(Swepub:lu)medf-pni (author)
  • Viigimaa, Margus (author)
  • Laurent, Stéphane (author)
  • Agabiti-Rosei, Enrico (author)
  • Wu, Zhaosu (author)
  • Zhu, Dingliang (author)
  • Rodicio, José Luis (author)
  • Ruilope, Luis Miguel (author)
  • Martell-Claros, Nieves (author)
  • Pinto, Fernando (author)
  • Schmieder, Roland E (author)
  • Burnier, Michel (author)
  • Banach, Maciej (author)
  • Cifkova, Renata (author)
  • Farsang, Csaba (author)
  • Konradi, Alexandra (author)
  • Lazareva, Irina (author)
  • Sirenko, Yuriy (author)
  • Dorobantu, Maria (author)
  • Postadzhiyan, Arman (author)
  • Accetto, Rok (author)
  • Jelakovic, Bojan (author)
  • Lovic, Dragan (author)
  • Manolis, Athanasios J (author)
  • Stylianou, Philippos (author)
  • Erdine, Serap (author)
  • Dicker, Dror (author)
  • Wei, Gangzhi (author)
  • Xu, Chengbin (author)
  • Xie, Hengge (author)
  • Coca, Antonio (author)
  • O'Brien, John (author)
  • Ford, Gary (author)
  • Internmedicin - epidemiologiForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Journal of Hypertension32:9, s. 1741-17501473-5598

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