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Heterogeneity of ma...
Heterogeneity of management practices surrounding operable gallbladder cancer – results of the OMEGA-S international HPB surgical survey
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- Balakrishnan, A. (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Jah, Asif (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Lesurtel, Mickael (author)
- Université Paris Cité,Beaujon Hospital
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- Andersson, B. (author)
- Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lever-, pankreas- och gallvägskirurgi,Forskargrupper vid Lunds universitet,Artificiell intelligens och thoraxkirurgisk vetenskap (AICTS),LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Hepato-Pancreato-Biliary Surgery,Lund University Research Groups,Artificial Intelligence in CardioThoracic Sciences (AICTS),LUCC: Lund University Cancer Centre,Other Strong Research Environments
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- Gibbs, Paul (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Harper, Simon J.F. (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Huguet, Emmanuel L. (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Kosmoliaptis, Vasilis (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Liau, Siong S. (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Praseedom, Raaj K. (author)
- Cambridge University Hospitals NHS Foundation Trust
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- Ramia, Jose M. (author)
- Alicante University General Hospital
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- Branes, Alejandro (author)
- Hospital Dr. Sótero del Río
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- Lendoire, Javier (author)
- University of Buenos Aires
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- Maithel, Shishir (author)
- Emory University
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- Serrablo, Alejandro (author)
- Miguel Servet University Hospital
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- Elsevier BV, 2022
- 2022
- English 7 s.
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In: HPB. - : Elsevier BV. - 1365-182X. ; 24:11, s. 2006-2012
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
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- Background: Gallbladder cancer (GBC) is an aggressive, uncommon malignancy, with variation in operative approaches adopted across centres and few large-scale studies to guide practice. We aimed to identify the extent of heterogeneity in GBC internationally to better inform the need for future multicentre studies. Methods: A 34-question online survey was disseminated to members of the European-African Hepatopancreatobiliary Association (EAHPBA), American Hepatopancreatobiliary Association (AHPBA) and Asia–Pacific Hepatopancreatobiliary Association (A-PHPBA) regarding practices around diagnostic workup, operative approach, utilization of neoadjuvant and adjuvant therapies and surveillance strategies. Results: Two hundred and three surgeons responded from 51 countries. High liver resection volume units (>50 resections/year) organised HPB multidisciplinary team discussion of GBCs more commonly than those with low volumes (p < 0.0001). Management practices exhibited areas of heterogeneity, particularly around operative extent. Contrary to consensus guidelines, anatomical liver resections were favoured over non-anatomical resections for T3 tumours and above, lymphadenectomy extent was lower than recommended, and a minority of respondents still routinely excised the common bile duct or port sites. Conclusion: Our findings suggest some similarities in the management of GBC internationally, but also specific areas of practice which differed from published guidelines. Transcontinental collaborative studies on GBC are necessary to establish evidence-based practice to minimise variation and optimise outcomes. © 2022 International Hepato-Pancreato-Biliary Association Inc.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Balakrishnan, A.
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Jah, Asif
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Lesurtel, Mickae ...
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Andersson, B.
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Gibbs, Paul
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Harper, Simon J. ...
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Huguet, Emmanuel ...
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Kosmoliaptis, Va ...
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Liau, Siong S.
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Praseedom, Raaj ...
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Ramia, Jose M.
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Branes, Alejandr ...
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Lendoire, Javier
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Maithel, Shishir
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Serrablo, Alejan ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
- Articles in the publication
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HPB
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HPB : the offici ...
- By the university
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Lund University
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Karolinska Institutet