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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004442naa a2200349 4500
001oai:lup.lub.lu.se:5e87b041-3ad8-41ee-8fa1-f73bb29022ac
003SwePub
008160401s2009 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/14752752 URI
024a https://doi.org/10.1186/1471-2474-10-992 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Ageberg, Eva4 aut
2451 0a Principles of brain plasticity in improving sensorimotor function of the knee and leg in healthy subjects: A double-blind randomized exploratory trial
264 c 2009-08-05
264 1b Springer Science and Business Media LLC,c 2009
520 a Background: Principles of brain plasticity is used in the treatment of patients with functional limitations to improve sensorimotor function. Training is included in the treatment of knee injury to improve both patient-reported function and sensorimotor function. However, impairment in sensorimotor function often persists despite training. Therefore, it was suggested that training programs need to be more effective to improve sensorimotor function after knee injury. The aim of the current study was to investigate if principles of brain plasticity that have been successfully used on the hand and foot to improve sensorimotor function can be applied on the knee. We hypothesized that temporary anesthesia of the skin area above and below the knee would improve sensorimotor function of the ipsilateral knee and leg. Methods: In this first double-blind exploratory study, 28 uninjured subjects (mean age 26 years, range 19-34, 50% women) were randomized to temporary local cutaneous application of anesthetic (EMLA (R)) (n=14) or placebo cream (n=14). Fifty grams of EMLA, or placebo, was applied on the leg 10 cm above and 10 cm below the center of patella, leaving the area around the knee without cream. Measures of sensory function (perception of touch, vibration sense, knee kinesthesia) and motor function (knee muscle strength, hop test) were assessed before and after 90 minutes of treatment with EMLA or placebo. The paired t-test was used for comparisons within groups and the independent t-test for comparisons between groups. The number of subjects needed was determined by an a priori sample size calculation. Results: No statistically significant or clinically relevant differences were seen over time (before vs. after) in the measures of sensory or motor functions in the EMLA group or in the placebo group. There were no differences between the groups due to treatment effect (EMLA vs. placebo). Conclusion: We found no effect of temporary cutaneous anesthesia on sensorimotor function of the ipsilateral knee and leg in uninjured subjects. The principles used in this study remain to be tested in subjects with knee injury.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng
700a Björkman, Andersu Lund University,Lunds universitet,Handkirurgi, Malmö,Forskargrupper vid Lunds universitet,Hand Surgery, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)hand-abj
700a Rosén, Birgittau Lund University,Lunds universitet,Handkirurgi, Malmö,Forskargrupper vid Lunds universitet,Hand Surgery, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)hand-bro
700a Lundborg, Göranu Lund University,Lunds universitet,Handkirurgi, Malmö,Forskargrupper vid Lunds universitet,Hand Surgery, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)hand-glu
700a Roos, Ewau Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-ero
710a Handkirurgi, Malmöb Forskargrupper vid Lunds universitet4 org
773t BMC Musculoskeletal Disordersd : Springer Science and Business Media LLCg 10q 10x 1471-2474
856u http://dx.doi.org/10.1186/1471-2474-10-99y FULLTEXT
856u https://bmcmusculoskeletdisord.biomedcentral.com/track/pdf/10.1186/1471-2474-10-99
8564 8u https://lup.lub.lu.se/record/1475275
8564 8u https://doi.org/10.1186/1471-2474-10-99

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By the author/editor
Ageberg, Eva
Björkman, Anders
Rosén, Birgitta
Lundborg, Göran
Roos, Ewa
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Orthopaedics
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BMC Musculoskele ...
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Lund University

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