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Aliased Flow Signal...
Aliased Flow Signal Planimetry by Cardiovascular Magnetic Resonance Imaging for Grading Aortic Stenosis Severity : A Prospective Pilot Study
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- Mantini, Cesare (author)
- University G.d'Annunzio of Chieti-Pescara
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- Khanji, Mohammed Y. (author)
- Queen Mary University,Barts Health NHS Trust,Newham University Hospital
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- D’ugo, Emilia (author)
- Azienda Sanitaria Locale 2 Abruzzo Chieti
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- Olivieri, Marzia (author)
- University G.d'Annunzio of Chieti-Pescara
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- Caputi, Cristiano Giovanni (author)
- Azienda Sanitaria Locale 2 Abruzzo Chieti
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- Bufano, Gabriella (author)
- University G.d'Annunzio of Chieti-Pescara
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- Mastrodicasa, Domenico (author)
- Stanford University School of Medicine
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- Garcia, Darien Calvo (author)
- University G.d'Annunzio of Chieti-Pescara
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- Rotondo, Domenico (author)
- Azienda Sanitaria Locale 2 Abruzzo Chieti
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- Candeloro, Matteo (author)
- University G.d'Annunzio of Chieti-Pescara
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- Tana, Claudio (author)
- Azienda Sanitaria Locale 2 Abruzzo Chieti
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- Cademartiri, Filippo (author)
- SDN IRCCS
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- Ionescu, Adrian (author)
- Swansea Bay University Health Board
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- Caulo, Massimo (author)
- University G.d'Annunzio of Chieti-Pescara
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- Gallina, Sabina (author)
- University G.d'Annunzio of Chieti-Pescara
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- Ricci, Fabrizio (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,University G.d'Annunzio of Chieti-Pescara
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University Gd'Annunzio of Chieti-Pescara Queen Mary University (creator_code:org_t)
- 2021-10-18
- 2021
- English.
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In: Frontiers in Cardiovascular Medicine. - : Frontiers Media SA. - 2297-055X. ; 8
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Abstract
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- Objectives: Transthoracic echocardiography (TTE) is the standard technique for assessing aortic stenosis (AS), with effective orifice area (EOA) recommended for grading severity. EOA is operator-dependent, influenced by a number of pitfalls and requires multiple measurements introducing independent and random sources of error. We tested the diagnostic accuracy and precision of aliased orifice area planimetry (AOAcmr ), a new, simple, non-invasive technique for grading of AS severity by low-VENC phase-contrast cardiovascular magnetic resonance (CMR) imaging. Methods: Twenty-two consecutive patients with mild, moderate, or severe AS and six age-and sex-matched healthy controls had TTE and CMR examinations on the same day. We performed analysis of agreement and correlation among (i) AOAcmr; (ii) geometric orifice area (GOAcmr ) by direct CMR planimetry; (iii) EOAecho by TTE-continuity equation; and (iv) the “gold standard” multimodality EOA (EOAhybrid ) obtained by substituting CMR LVOT area into Doppler continuity equation. Results: There was excellent pairwise positive linear correlation among AOAcmr, EOAhybrid, GOAcmr, and EOAecho (p < 0.001); AOAcmr had the highest correlation with EOAhybrid (R2 = 0.985, p < 0.001). There was good agreement between methods, with the lowest bias (0.019) for the comparison between AOAcmr and EOAhybrid . AOAcmr yielded excellent intra-and inter-rater reliability (intraclass correlation coefficient: 0.997 and 0.998, respectively). Conclusions: Aliased orifice area planimetry by 2D phase contrast imaging is a simple, reproducible, accurate “one-stop shop” CMR method for grading AS, potentially useful when echocardiographic severity assessment is inconclusive or discordant. Larger studies are warranted to confirm and validate these promising preliminary results.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Aliasing analysis
- Aortic stenosis (AS)
- CMR
- Echocardiography
- Phase contrast (PC)
- Valvular heart disease
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Mantini, Cesare
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Khanji, Mohammed ...
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D’ugo, Emilia
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Olivieri, Marzia
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Caputi, Cristian ...
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Bufano, Gabriell ...
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show more...
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Mastrodicasa, Do ...
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Garcia, Darien C ...
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Rotondo, Domenic ...
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Candeloro, Matte ...
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Tana, Claudio
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Cademartiri, Fil ...
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Ionescu, Adrian
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Caulo, Massimo
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Gallina, Sabina
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Ricci, Fabrizio
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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Frontiers in Car ...
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Lund University