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Bringing Advanced T...
Bringing Advanced Therapies for Parkinson's Disease to the Clinic : The Scientist's Perspective
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- Tomishima, Mark (author)
- BlueRock Therapeutics
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- Kirkeby, Agnete (author)
- Lund University,Lunds universitet,WCMM- Wallenberg center för molekylär medicinsk forskning,Medicinska fakulteten,WCMM-Wallenberg Centre for Molecular Medicine,Faculty of Medicine,University of Copenhagen
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(creator_code:org_t)
- IOS Press, 2021
- 2021
- English.
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In: Journal of Parkinson's Disease. - : IOS Press. - 1877-7171 .- 1877-718X. ; 11:s2, s. 135-140
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Abstract
Subject headings
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- After many years of preclinical development, cell and gene therapies have advanced from research tools in the lab to clinical-grade products for patients, and today they constitute more than a quarter of all new Phase I clinical trials for Parkinson's disease. Whereas efficacy has been convincingly proven for many of these products in preclinical models, the field is now entering a new phase where the functionality and safety of these products will need to stand the test in clinical trials. If successful, these new products can have the potential to provide patients with a one-time administered treatment which may alleviate them from daily symptomatic dopaminergic medication.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- ATMP
- clinical trial
- dopaminergic neurons
- regenerative therapy
- stem cells
- transplantation
Publication and Content Type
- for (subject category)
- ref (subject category)
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