Search: onr:"swepub:oai:lup.lub.lu.se:630cbb5a-d9c4-4ed1-be22-870191a81057" > Bichir HoxA cluster...
Fältnamn | Indikatorer | Metadata |
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000 | 03056naa a2200445 4500 | |
001 | oai:lup.lub.lu.se:630cbb5a-d9c4-4ed1-be22-870191a81057 | |
003 | SwePub | |
008 | 160401s2004 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/2900962 URI |
024 | 7 | a https://doi.org/10.1101/gr.17129042 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Chiu, CH4 aut |
245 | 1 0 | a Bichir HoxA cluster sequence reveals surprising trends in ray-finned fish genomic evolution |
264 | c 2004-01-05 | |
264 | 1 | b Cold Spring Harbor Laboratory,c 2004 |
520 | a The study of Hox clusters and genes provides insights into the evolution of genomic regulation of development. Derived ray-finned fishes (Actinopterygii, Teleostei) such as zebrafish and pufferfish possess duplicated Hox clusters that have undergone considerable sequence evolution. Whether these changes are associated with the duplication(s) that produced extra Hox clusters is unresolved because comparison with basal lineages is unavailable. We sequenced and analyzed the HoxA cluster of the bichir (Polypterus senegalus), a phylogenetically basal actinopterygian. Independent lines of evidence indicate that bichir has one HoxA cluster that is mosaic in its patterns of noncoding sequence conservation and gene retention relative to the HoxA clusters of human and shark, and the HoxAalpha and HoxAbeta clusters of zebrafish, pufferfish, and striped bass. HoxA cluster noncoding sequences conserved between bichir and euteleosts indicate that novel cis-sequences were acquired in the stem actinopterygians and maintained after cluster duplication. Hence, in the earliest actinopterygians, evolution of the single HoxA cluster was already more dynamic than in human and shark. This tendency peaked among teleosts after HoxA cluster duplication. | |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
700 | 1 | a Dewar, K4 aut |
700 | 1 | a Wagner, GP4 aut |
700 | 1 | a Takahashi, K4 aut |
700 | 1 | a Ruddle, F4 aut |
700 | 1 | a Ledje, Christinau Lund University,Lunds universitet,Biologiska institutionen,Naturvetenskapliga fakulteten,Department of Biology,Faculty of Science4 aut0 (Swepub:lu)gen-cle |
700 | 1 | a Bartsch, P4 aut |
700 | 1 | a Scemama, JL4 aut |
700 | 1 | a Stellwag, E4 aut |
700 | 1 | a Fried, C4 aut |
700 | 1 | a Prohaska, SJ4 aut |
700 | 1 | a Stadler, PF4 aut |
700 | 1 | a Amemiya, CT4 aut |
710 | 2 | a Biologiska institutionenb Naturvetenskapliga fakulteten4 org |
773 | 0 | t Genome Researchd : Cold Spring Harbor Laboratoryg 14:1, s. 11-17q 14:1<11-17x 1549-5469x 1088-9051 |
856 | 4 | u http://dx.doi.org/10.1101/gr.1712904x freey FULLTEXT |
856 | 4 | u http://genome.cshlp.org/content/14/1/11.full.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/290096 |
856 | 4 8 | u https://doi.org/10.1101/gr.1712904 |
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