SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:lup.lub.lu.se:64b9c182-1a48-4703-b4d0-907aaf398b03"
 

Search: onr:"swepub:oai:lup.lub.lu.se:64b9c182-1a48-4703-b4d0-907aaf398b03" > The Association Bet...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Zamora-Ros, Raul (author)

The Association Between Dietary Flavonoid and Lignan Intakes and Incident Type 2 Diabetes in European Populations The EPIC-InterAct study

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • 2013-11-13
  • American Diabetes Association,2013

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:64b9c182-1a48-4703-b4d0-907aaf398b03
  • https://lup.lub.lu.se/record/4273300URI
  • https://doi.org/10.2337/dc13-0877DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • OBJECTIVETo study the association between dietary flavonoid and lignan intakes, and the risk of development of type 2 diabetes among European populations.RESEARCH DESIGN AND METHODSThe European Prospective Investigation into Cancer and Nutrition-InterAct case-cohort study included 12,403 incident type 2 diabetes cases and a stratified subcohort of 16,154 participants from among 340,234 participants with 3.99 million person-years of follow-up in eight European countries. At baseline, country-specific validated dietary questionnaires were used. A flavonoid and lignan food composition database was developed from the Phenol-Explorer, the U.K. Food Standards Agency, and the U.S. Department of Agriculture databases. Hazard ratios (HRs) from country-specific Prentice-weighted Cox regression models were pooled using random-effects meta-analysis.RESULTSIn multivariable models, a trend for an inverse association between total flavonoid intake and type 2 diabetes was observed (HR for the highest vs. the lowest quintile, 0.90 [95% CI 0.77-1.04]; P value trend = 0.040), but not with lignans (HR 0.88 [95% CI 0.72-1.07]; P value trend = 0.119). Among flavonoid subclasses, flavonols (HR 0.81 [95% CI 0.69-0.95]; P value trend = 0.020) and flavanols (HR 0.82 [95% CI 0.68-0.99]; P value trend = 0.012), including flavan-3-ol monomers (HR 0.73 [95% CI 0.57-0.93]; P value trend = 0.029), were associated with a significantly reduced hazard of diabetes.CONCLUSIONSProspective findings in this large European cohort demonstrate inverse associations between flavonoids, particularly flavanols and flavonols, and incident type 2 diabetes. This suggests a potential protective role of eating a diet rich in flavonoids, a dietary pattern based on plant-based foods, in the prevention of type 2 diabetes.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Forouhi, Nita G. (author)
  • Sharp, Stephen J. (author)
  • Gonzalez, Carlos A. (author)
  • Buijsse, Brian (author)
  • Guevara, Marcela (author)
  • van der Schouw, Yvonne T. (author)
  • Amiano, Pilar (author)
  • Boeing, Heiner (author)
  • Bredsdorff, Lea (author)
  • Clavel-Chapelon, Francoise (author)
  • Fagherazzi, Guy (author)
  • Feskens, Edith J. (author)
  • Franks, PaulLund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups(Swepub:lu)med-plf (author)
  • Grioni, Sara (author)
  • Katzke, Verena (author)
  • Key, Timothy J. (author)
  • Khaw, Kay-Tee (author)
  • Kuehn, Tilman (author)
  • Masala, Giovanna (author)
  • Mattiello, Amalia (author)
  • Molina-Montes, Esther (author)
  • Nilsson, PeterLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups(Swepub:lu)medf-pni (author)
  • Overvad, Kim (author)
  • Perquier, Florence (author)
  • Ramon Quiros, J. (author)
  • Romieu, Isabelle (author)
  • Sacerdote, Carlotta (author)
  • Scalbert, Augustin (author)
  • Schulze, Matthias (author)
  • Slimani, Nadia (author)
  • Spijkerman, Annemieke M. W. (author)
  • Tjonneland, Anne (author)
  • Jose Tormo, Maria (author)
  • Tumino, Rosario (author)
  • van der A, Daphne L. (author)
  • Langenberg, Claudia (author)
  • Riboli, Elio (author)
  • Wareham, Nicholas J. (author)
  • Genetisk och molekylär epidemiologiForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Diabetes Care: American Diabetes Association36:12, s. 3961-39701935-55480149-5992

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view