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Diagnosis, monitori...
Diagnosis, monitoring and prevention of exposure-related non-communicable diseases in the living and working environment : DiMoPEx-project is designed to determine the impacts of environmental exposure on human health
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- Budnik, Lygia Therese (author)
- University Medical Center Hamburg-Eppendorf
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- Adam, Balazs (author)
- University of Debrecen
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- Albin, Maria (author)
- Karolinska Institutet,Karolinska Institute,Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine
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- Banelli, Barbara (author)
- Ospedale Policlinico San Martino,University of Genoa
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- Baur, Xaver (author)
- European Society for Environmental and Occupational Medicine
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- Belpoggi, Fiorella (author)
- Ramazzini Institute
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- Bolognesi, Claudia (author)
- Ospedale Policlinico San Martino
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- Broberg, Karin (author)
- Karolinska Institutet,Karolinska Institute
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- Gustavsson, Per (author)
- Karolinska Institutet,Karolinska Institute
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- Göen, Thomas (author)
- Friedrich-Alexander University Erlangen-Nürnberg
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- Fischer, Axel (author)
- Charité - University Medicine Berlin
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Jarosinska, Dorota (author)
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Manservisi, Fabiana (author)
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- O'Kennedy, Richard (author)
- Dublin City University
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- Øvrevik, Johan (author)
- Norwegian Institute of Public Health
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Paunovic, Elizabet (author)
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Ritz, Beate (author)
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- Scheepers, Paul T.J. (author)
- Radboud University Nijmegen
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- Schlünssen, Vivi (author)
- Aarhus University
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- Schwarzenbach, Heidi (author)
- University Medical Center Hamburg-Eppendorf
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- Schwarze, Per E. (author)
- Norwegian Institute of Public Health
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- Sheils, Orla (author)
- Trinity College Dublin
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- Sigsgaard, Torben (author)
- Aarhus University
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- Van Damme, Karel (author)
- Catholic University of Leuven
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- Casteleyn, Ludwine (author)
- Catholic University of Leuven
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(creator_code:org_t)
- 2018-02-05
- 2018
- English 22 s.
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In: Journal of Occupational Medicine and Toxicology. - : Springer Science and Business Media LLC. - 1745-6673. ; 13:1
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https://occup-med.bi...
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Abstract
Subject headings
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- The WHO has ranked environmental hazardous exposures in the living and working environment among the top risk factors for chronic disease mortality. Worldwide, about 40 million people die each year from noncommunicable diseases (NCDs) including cancer, diabetes, and chronic cardiovascular, neurological and lung diseases. The exposure to ambient pollution in the living and working environment is exacerbated by individual susceptibilities and lifestyle-driven factors to produce complex and complicated NCD etiologies. Research addressing the links between environmental exposure and disease prevalence is key for prevention of the pandemic increase in NCD morbidity and mortality. However, the long latency, the chronic course of some diseases and the necessity to address cumulative exposures over very long periods does mean that it is often difficult to identify causal environmental exposures. EU-funded COST Action DiMoPEx is developing new concepts for a better understanding of health-environment (including gene-environment) interactions in the etiology of NCDs. The overarching idea is to teach and train scientists and physicians to learn how to include efficient and valid exposure assessments in their research and in their clinical practice in current and future cooperative projects. DiMoPEx partners have identified some of the emerging research needs, which include the lack of evidence-based exposure data and the need for human-equivalent animal models mirroring human lifespan and low-dose cumulative exposures. Utilizing an interdisciplinary approach incorporating seven working groups, DiMoPEx will focus on aspects of air pollution with particulate matter including dust and fibers and on exposure to low doses of solvents and sensitizing agents. Biomarkers of early exposure and their associated effects as indicators of disease-derived information will be tested and standardized within individual projects. Risks arising from some NCDs, like pneumoconioses, cancers and allergies, are predictable and preventable. Consequently, preventative action could lead to decreasing disease morbidity and mortality for many of the NCDs that are of major public concern. DiMoPEx plans to catalyze and stimulate interaction of scientists with policy-makers in attacking these exposure-related diseases.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- Environmental/occupational exposure to xenobiotics
- Human biomonitoring
- Noncommunicable diseases
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- By the author/editor
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Budnik, Lygia Th ...
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Adam, Balazs
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Albin, Maria
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Banelli, Barbara
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Baur, Xaver
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Belpoggi, Fiorel ...
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show more...
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Bolognesi, Claud ...
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Broberg, Karin
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Gustavsson, Per
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Göen, Thomas
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Fischer, Axel
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Jarosinska, Doro ...
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Manservisi, Fabi ...
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O'Kennedy, Richa ...
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Øvrevik, Johan
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Paunovic, Elizab ...
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Ritz, Beate
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Scheepers, Paul ...
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Schlünssen, Vivi
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Schwarzenbach, H ...
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Schwarze, Per E.
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Sheils, Orla
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Sigsgaard, Torbe ...
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Van Damme, Karel
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Casteleyn, Ludwi ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
- Articles in the publication
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Journal of Occup ...
- By the university
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Lund University
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Karolinska Institutet