Search: onr:"swepub:oai:lup.lub.lu.se:69d98da1-2b4d-41c6-a897-86d21dc0f8e7" >
Inheritable molecul...
Inheritable molecular variants of moderate and mild hemophilia A
-
- Ljung, R (author)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pediatrisk hematologi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Paediatric Haematology Research Unit,Lund University Research Groups
-
- Holmberg, Lars (author)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
-
Nilsson, Inga Marie (author)
-
(creator_code:org_t)
- 1981
- 1981
- English 6 s.
-
In: Acta Medica Scandinavica. - 0001-6101. ; 209:1-2, s. 11-16
- Related links:
-
https://lup.lub.lu.s...
Abstract
Subject headings
Close
- Factor VIII clotting activity (VIII:C) and factor VIII clotting antigen (VIII:CAg) were investigated in 54 patients with hemophilia A of moderate or mild severity. The patients belonged to 28 kindreds. The study showed a genetically determined molecular variation within hemophilia A of both moderate and mild forms. Each form can be classified into 3 types according to the content of demonstrable VIII:CAg. Type I has no demonstrable VIII:CAg, type IIa has VIII:CAg in an amount smaller than, or approximately equal to, that of VIII:C and type IIb has a larger amount of VIII:CAg than VIII:C. Affected members of one and the same kindred always have the same type of the disease.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Keyword
- Antigens
- Blood Coagulation Tests
- Factor VIII
- Female
- Genetic Variation
- Hemophilia A
- Humans
- Male
- Pedigree
- Radioimmunoassay
- Journal Article
- Research Support, Non-U.S. Gov't
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database