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Molecular cloning o...
Molecular cloning of a small prostate protein, known as beta-microsemenoprotein, PSP94 or beta-inhibin, and demonstration of transcripts in non-genital tissues
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Ulvsbäck, M. (author)
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Lindstrom, C. (author)
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- Weiber, Håkan (author)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Abrahamsson, Per-Anders (author)
- Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine
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- Lilja, Hans (author)
- Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups
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- Lundwall, Åke (author)
- Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups
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(creator_code:org_t)
- 1989
- 1989
- English.
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In: Biochem Biophys Res Commun. ; 164:3, s. 5-1310
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http://www.ncbi.nlm.... (free)
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Abstract
Subject headings
Close
- In order to study the gene expression of the seminal plasma protein beta-microseminoprotein, also known as PSP94 and beta-inhibin, clones encoding this protein were isolated from a cDNA library constructed in lambda gt11. Nucleotide sequencing confirmed the structure of a previously cloned cDNA. By northern blot analysis identical sized transcripts were demonstrated in the prostate, the respiratory (tracheal, bronchial and lung) tissues and the antrum part of the gastric mucosa. Thus, the protein is not primarily associated with male reproductive function. Although probably of no physiological significance, a slight structural similarity to the ovarian inhibin beta-chains was identified in the C-terminal half of the molecule.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Läkemedelskemi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medicinal Chemistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Prostate/*metabolism
- Peptides/*genetics
- Organ Specificity
- Oligonucleotide Probes/chemical synthesis
- Molecular Sequence Data
- Male
- Inhibins/genetics
- Humans
- Gene Library
- DNA/*genetics
- Comparative Study
- Molecular
- *Cloning
- Northern
- Blotting
- Amino Acid Sequence
- Base Sequence
- *Prostatic Secretory Proteins
- Proteins/*genetics
- Research Support
- Non-U.S. Gov't
- Seminal Plasma Proteins
- Sequence Homology
- Nucleic Acid
- *Transcription
- Genetic
Publication and Content Type
- art (subject category)
- ref (subject category)
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