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Search: onr:"swepub:oai:lup.lub.lu.se:7b701deb-ebfa-4d05-8e22-f945bf3d5993" > Prediction of Hospi...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007392naa a2200829 4500
001oai:lup.lub.lu.se:7b701deb-ebfa-4d05-8e22-f945bf3d5993
003SwePub
008221227s2022 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:148858603
0247 a https://lup.lub.lu.se/record/7b701deb-ebfa-4d05-8e22-f945bf3d59932 URI
0247 a https://doi.org/10.1002/acr.245042 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1488586032 URI
040 a (SwePub)lud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Legge, Alexandrau Dalhousie University4 aut
2451 0a Prediction of Hospitalizations in Systemic Lupus Erythematosus Using the Systemic Lupus International Collaborating Clinics Frailty Index
264 c 2022-02-17
264 1b Wiley,c 2022
300 a 10 s.
520 a Objective: The Systemic Lupus International Collaborating Clinics (SLICC) frailty index (FI) predicts mortality and damage accrual in systemic lupus erythematosus (SLE), but its association with hospitalizations has not been described. Our objective was to estimate the association of baseline SLICC-FI values with future hospitalizations in the SLICC inception cohort. Methods: Baseline SLICC-FI scores were calculated. The number and duration of inpatient hospitalizations during follow-up were recorded. Negative binomial regression was used to estimate the association between baseline SLICC-FI values and the rate of hospitalizations per patient-year of follow-up. Linear regression was used to estimate the association of baseline SLICC-FI scores with the proportion of follow-up time spent in the hospital. Multivariable models were adjusted for relevant baseline characteristics. Results: The 1,549 patients with SLE eligible for this analysis were mostly female (88.7%), with a mean ± SD age of 35.7 ± 13.3 years and a median disease duration of 1.2 years (interquartile range 0.9–1.5) at baseline. Mean ± SD baseline SLICC-FI was 0.17 ± 0.08. During mean ± SD follow-up of 7.2 ± 3.7 years, 614 patients (39.6%) experienced 1,570 hospitalizations. Higher baseline SLICC-FI values (per 0.05 increment) were associated with more frequent hospitalizations during follow-up, with an incidence rate ratio of 1.21 (95% confidence interval [95% CI] 1.13–1.30) after adjustment for baseline age, sex, glucocorticoid use, immunosuppressive use, ethnicity/location, SLE Disease Activity Index 2000 score, SLICC/American College of Rheumatology Damage Index score, and disease duration. Among patients with ≥1 hospitalization, higher baseline SLICC-FI values predicted a greater proportion of follow-up time spent hospitalized (relative rate 1.09 [95% CI 1.02–1.16]). Conclusion: The SLICC-FI predicts future hospitalizations among incident SLE patients, further supporting the SLICC-FI as a valid health measure in SLE.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
7001 a Kirkland, Susanu Dalhousie University4 aut
7001 a Rockwood, Kennethu Dalhousie University4 aut
7001 a Andreou, Pantelisu Dalhousie University4 aut
7001 a Bae, Sang Cheolu Hanyang University Hospital for Rheumatic Disease4 aut
7001 a Gordon, Carolineu University of Birmingham4 aut
7001 a Romero-Diaz, Juanitau Salvador Zubirán National Institute of Health Sciences and Nutrition4 aut
7001 a Sanchez-Guerrero, Jorgeu Salvador Zubirán National Institute of Health Sciences and Nutrition4 aut
7001 a Wallace, Daniel J.u University of California, Los Angeles4 aut
7001 a Bernatsky, Sashau McGill University4 aut
7001 a Clarke, Ann E.u Cumming School of Medicine4 aut
7001 a Merrill, Joan T.u Oklahoma Medical Research Foundation4 aut
7001 a Ginzler, Ellen M.u SUNY Downstate Health Sciences University,Feinstein Institute for Medical Research4 aut
7001 a Fortin, Paul R.u Centre hospitalier universitaire de Québec4 aut
7001 a Gladman, Dafna D.u University of Toronto4 aut
7001 a Urowitz, Murray B.u University of Toronto4 aut
7001 a Bruce, Ian N.u University of Manchester4 aut
7001 a Isenberg, David A.u University College London,Indian Institute of Technology4 aut
7001 a Rahman, Anisuru University College London4 aut
7001 a Alarcón, Graciela S.u University of Alabama4 aut
7001 a Petri, Michelleu Johns Hopkins University School of Medicine4 aut
7001 a Khamashta, Munther A.u St Thomas' Hospital4 aut
7001 a Dooley, M. A.u University of North Carolina4 aut
7001 a Ramsey-Goldman, Rosalindu Northwestern University Feinberg School of Medicine4 aut
7001 a Manzi, Susanu Allegheny Health Network4 aut
7001 a Zoma, Asad A.u Hairmyres Hospital4 aut
7001 a Aranow, Cynthiau Feinstein Institute for Medical Research4 aut
7001 a Mackay, Megganu Feinstein Institute for Medical Research4 aut
7001 a Ruiz-Irastorza, Guillermou Biocruces Bizkaia Health Research Institute4 aut
7001 a Lim, S. Samu Emory University4 aut
7001 a Inanc, Murat4 aut
7001 a van Vollenhoven, Ronald F.u Karolinska Institute4 aut
7001 a Jonsen, Andreasu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund SLE Research Group,Forskargrupper vid Lunds universitet,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)reum-ajo
7001 a Nived, Olau Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-oni
7001 a Ramos-Casals, Manuelu Hospital Clínic of Barcelona4 aut
7001 a Kamen, Diane L.u Medical University of South Carolina4 aut
7001 a Kalunian, Kenneth C.u University of California, San Diego4 aut
7001 a Jacobsen, Sørenu Copenhagen University Hospital4 aut
7001 a Peschken, Christine A.u University of Manitoba4 aut
7001 a Askanase, Ancau Indian Institute of Technology4 aut
7001 a Hanly, John G.u Dalhousie University4 aut
7102 a Dalhousie Universityb Hanyang University Hospital for Rheumatic Disease4 org
7730 t Arthritis Care and Researchd : Wileyg 74:4, s. 638-647q 74:4<638-647x 2151-464Xx 2151-4658
8564 u http://dx.doi.org/10.1002/acr.24504y FULLTEXT
8564 u https://www.research.manchester.ac.uk/portal/en/publications/prediction-of-hospitalizations-in-systemic-lupus-erythematosus-using-the-systemic-lupus-international-collaborating-clinics-frailty-index-sliccfi(cba40d6d-d22d-4843-b9b0-159b6787795d).html
8564 8u https://lup.lub.lu.se/record/7b701deb-ebfa-4d05-8e22-f945bf3d5993
8564 8u https://doi.org/10.1002/acr.24504
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:148858603

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