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Feasibility and saf...
Feasibility and safety of synchrotron-based X-ray phase contrast imaging as a technique complementary to histopathology analysis
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- Li, Kan Yan Chloe (author)
- University College London
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- Dejea, Hector (author)
- Lund University,Lunds universitet,Avdelningen för Biomedicinsk teknik,Institutionen för biomedicinsk teknik,Institutioner vid LTH,Lunds Tekniska Högskola,MAX IV-laboratoriet,Department of Biomedical Engineering,Departments at LTH,Faculty of Engineering, LTH,MAX IV Laboratory,ETH Zürich,Paul Scherrer Institute
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- De Winne, Koen (author)
- Antwerp University Hospital
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- Bonnin, Anne (author)
- Paul Scherrer Institute
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- D’Onofrio, Valentino (author)
- Hasselt University
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- Cox, Janneke A. (author)
- Hasselt University
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- Garcia-Canadilla, Patricia (author)
- University of Barcelona
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- Lammens, Martin (author)
- Antwerp University Hospital
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- Cook, Andrew C. (author)
- University College London
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- Bijnens, Bart (author)
- Catalan Institution for Research and Advanced Studies,Institutd' Investigacions Biomèdiques August Pi iSunyer (IDIBAPS)
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- Dendooven, Amélie (author)
- Antwerp University Hospital,Hasselt University
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(creator_code:org_t)
- 2023
- 2023
- English 13 s.
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In: Histochemistry and Cell Biology. - 0948-6143. ; 160:5, s. 377-389
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Abstract
Subject headings
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- X-ray phase contrast imaging (X-PCI) is a powerful technique for high-resolution, three-dimensional imaging of soft tissue samples in a non-destructive manner. In this technical report, we assess the quality of standard histopathological techniques performed on formalin-fixed, paraffin-embedded (FFPE) human tissue samples that have been irradiated with different doses of X-rays in the context of an X-PCI experiment. The data from this study demonstrate that routine histochemical and immunohistochemical staining quality as well as DNA and RNA analyses are not affected by previous X-PCI on human FFPE samples. From these data we conclude it is feasible and acceptable to perform X-PCI on FFPE human biopsies.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
Keyword
- Needle biopsies
- Pathology
- X-ray phase contrast imaging
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Li, Kan Yan Chlo ...
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Dejea, Hector
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De Winne, Koen
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Bonnin, Anne
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D’Onofrio, Valen ...
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Cox, Janneke A.
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show more...
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Garcia-Canadilla ...
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Lammens, Martin
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Cook, Andrew C.
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Bijnens, Bart
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Dendooven, Améli ...
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show less...
- About the subject
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Medical Engineer ...
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and Medical Image Pr ...
- Articles in the publication
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Histochemistry a ...
- By the university
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Lund University