Search: onr:"swepub:oai:lup.lub.lu.se:80c6cd1f-726e-4b77-8c3e-2a6ba93ebc1a" >
Fracture Risk Asses...
Fracture Risk Assessment in Older Adults Using a Combination of Selected Quantitative Computed Tomography Bone Measures: A Subanalysis of the Age, Gene/Environment Susceptibility-Reykjavik Study
-
Rianon, Nahid J. (author)
-
Lang, Thomas F. (author)
-
Siggeirsdottir, Kristin (author)
-
show more...
-
Sigurdsson, Gunnar (author)
-
Eiriksdottir, Gudny (author)
-
Sigurdsson, Sigurdur (author)
-
- Jonsson, Brynjolfur (author)
- Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups
-
Garcia, Melissa (author)
-
Yu, Binbing (author)
-
Kapadia, Asha S. (author)
-
Taylor, Wendell C. (author)
-
Selwyn, Beatrice J. (author)
-
Gudnason, Vilmundur (author)
-
Launer, Lenore J. (author)
-
Harris, Tamara B. (author)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2014
- 2014
- English.
-
In: Journal of Clinical Densitometry. - : Elsevier BV. - 1094-6950. ; 17:1, s. 25-31
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://europepmc.or...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Bone mineral density (BMD) and geometric bone measures are individually associated with prevalent osteoporotic fractures. Whether an aggregate of these measures would better associate with fractures has not been examined. We examined relationships between self-reported fractures and selected bone measures acquired by quantitative computerized tomography (QCT), a composite bone score, and QCT-acquired dual-energy X-ray absorptiometry-like total femur BMD in 2110 men and 2682 women in the Age, Gene/Environment Susceptibility-Reykjavik Study. The combined bone score was generated by summing gender-specific Z-scores for 4 QCT measures: vertebral trabecular BMD, femur neck cortical thickness, femur neck trabecular BMD, and femur neck minimal cross-sectional area. Except for the latter measure, lower scores for QCT measures, singly and combined, showed positive (p < 0.05) associations with fractures. Results remained the same in stratified models for participants not taking bone-promoting medication. In women on bone-promoting medication, greater femur neck cortical thickness and trabecular BMD were significantly associated with fracture status. However, the association between fracture and combined bone score was not stronger than the associations between fracture and individual measures or total femur BMD. Thus, the selected measures did not all similarly associate with fracture status and did not appear to have an additive effect on fracture status.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Keyword
- Bone mineral density
- bone strength
- elderly
- fracture
- quantitative
- computerized tomography
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Rianon, Nahid J.
-
Lang, Thomas F.
-
Siggeirsdottir, ...
-
Sigurdsson, Gunn ...
-
Eiriksdottir, Gu ...
-
Sigurdsson, Sigu ...
-
show more...
-
Jonsson, Brynjol ...
-
Garcia, Melissa
-
Yu, Binbing
-
Kapadia, Asha S.
-
Taylor, Wendell ...
-
Selwyn, Beatrice ...
-
Gudnason, Vilmun ...
-
Launer, Lenore J ...
-
Harris, Tamara B ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Orthopaedics
- Articles in the publication
-
Journal of Clini ...
- By the university
-
Lund University