Solute transfer in on-line analytical flow-through dialyzers

• Mass transfer in infinite parallel-plate dialyzers with co-flow between sample and detector streams is discussed for three different theoretical models. Analytical solutions with coupled diffusion and membrane transfer equations were obtained for plug flow in both channels. The finite-difference approximation method was used to obtain numerical solutions for a laminar-flow regime. Results obtained with a mixing-cup model under steady-state conditions were also included. With the dimensions typical for analytical dialyzers, there were only small differences between the laminar-flow and plug-flow models. The mixing-cup model predicted higher fluxes through the membrane than the other two models, particularly when the channel heights were increased. The theoretical results were compared with experimental results for dialysis of zinc(II) ions and the flow dependence agreed reasonably well with theory provided that the hydrostatic pressures were equal on both sides, and that stresses which could result in membrane bulging were kept low.Download full text in PDF

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Kemiteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Chemical Engineering (hsv//eng)

Publication and Content Type

art (subject category)

ref (subject category)