Search: onr:"swepub:oai:lup.lub.lu.se:87a95ce0-6837-4d27-a190-39587a26ee6d" >
Traditional and Dis...
Traditional and Disease-Specific Risk Factors for Cardiovascular Events in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis : A Multinational Retrospective Study
-
- Moiseev, Sergey (author)
- I.M. Sechenov First Moscow State Medical University
-
- Bulanov, Nikolay (author)
- I.M. Sechenov First Moscow State Medical University
-
Crnogorac, Matija (author)
-
show more...
-
- Direskeneli, Haner (author)
- Marmara University Hospital
-
Galesic, Kresimir (author)
-
- Gazel, Ummugulsum (author)
- Marmara University Hospital
-
- Geetha, Duvuru (author)
- Johns Hopkins University
-
- Guillevin, Loic (author)
- Cochin Hospital
-
- Hruškova, Zdenka (author)
- General University Hospital in Prague
-
- Little, Mark A. (author)
- Tallaght University Hospital
-
- O'Neill, Liam (author)
- Galway University Hospital
-
Makarov, Egor (author)
-
- McAdoo, Stephen P. (author)
- Imperial College London
-
- Mohammad, Aladdin J. (author)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund Vasculitis Epidemiology Research Group,Forskargrupper vid Lunds universitet,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Addenbrooke's Hospital,Cambridge University Hospitals NHS Foundation Trust
-
- Moran, Sarah (author)
- Trinity Translational Medicine Institute
-
- Novikov, Pavel (author)
- I.M. Sechenov First Moscow State Medical University
-
- Pusey, Charles D. (author)
- Imperial College London
-
- Rahmattulla, Chinar (author)
- Trinity Translational Medicine Institute
-
- Satrapova, Veronika (author)
- General University Hospital in Prague
-
- Silva, Joana (author)
- Imperial College London
-
- Suvorov, Alexander (author)
- Leiden University Medical Centre
-
- Tesar, Vladimir (author)
- General University Hospital in Prague
-
- Terrier, Benjamin (author)
- Cochin Hospital
-
- Willeit, Peter (author)
- I.M. Sechenov First Moscow State Medical University,Medical University of Innsbruck
-
Zhao, Ming Hui (author)
-
Kronbichler, Andreas (author)
-
Jayne, David R.W. (author)
-
show less...
-
IM. Sechenov First Moscow State Medical University Marmara University Hospital (creator_code:org_t)
- 2023-01-15
- 2023
- English 7 s.
-
In: Journal of Rheumatology. - : The Journal of Rheumatology. - 0315-162X .- 1499-2752. ; 50:9, s. 1145-1151
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://lup.lub.lu.s...
-
https://doi.org/10.3...
-
show less...
Abstract
Subject headings
Close
- Objective. To investigate the occurrence of cardiovascular events (CVEs) in a large cohort of patients with antineutrophil cytoplasmic antibody (ANCA)-Associated vasculitis (AAV) across the European Union, China, Turkey, Russia, the United Kingdom, and the USA. Methods. Patients with a definite diagnosis of AAV who were followed for ? 3 months and had sufficient documentation were included. Data on myocardial infarction (MI) and stroke were collected retrospectively from tertiary vasculitis centers. Univariate and multivariate Cox regression models were used to estimate hazard ratios (HRs) and 95% CIs. Results. Over a median follow-up of 62.0 months (IQR 22.6-100.0), CVEs (mostly MIs) occurred in 245 (10.7%) of 2286 patients with AAV, with a higher frequency in China and the UK. On multivariate regression analysis, older age (55-64.9 yrs, HR 2.93, 95% CI 1.99-4.31), smoking (HR 1.98, 95% CI 1.48-2.64), Chinese origin (HR 4.24, 95% CI 3.07-5.85), and pulmonary (HR 1.50, 95% CI 1.09-2.06) and kidney (HR 3.02, 95% CI 2.08-4.37) involvement were independent variables associated with a higher occurrence of CVEs. Conclusion. We showed that geographic region and both traditional and disease-specific (kidney involvement in particular) factors were independently associated with CVEs. Proper assessment and management of modifiable cardiovascular (CV) risk factors are essential for prevention of CV morbidity in patients with AAV.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Keyword
- ANCA-Associated vasculitis
- cardiovascular events
- myocardial infarction
- risk factors
- stroke
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Moiseev, Sergey
-
Bulanov, Nikolay
-
Crnogorac, Matij ...
-
Direskeneli, Han ...
-
Galesic, Kresimi ...
-
Gazel, Ummugulsu ...
-
show more...
-
Geetha, Duvuru
-
Guillevin, Loic
-
Hruškova, Zdenka
-
Little, Mark A.
-
O'Neill, Liam
-
Makarov, Egor
-
McAdoo, Stephen ...
-
Mohammad, Aladdi ...
-
Moran, Sarah
-
Novikov, Pavel
-
Pusey, Charles D ...
-
Rahmattulla, Chi ...
-
Satrapova, Veron ...
-
Silva, Joana
-
Suvorov, Alexand ...
-
Tesar, Vladimir
-
Terrier, Benjami ...
-
Willeit, Peter
-
Zhao, Ming Hui
-
Kronbichler, And ...
-
Jayne, David R.W ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Rheumatology and ...
- Articles in the publication
-
Journal of Rheum ...
- By the university
-
Lund University