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The European Vascul...
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Bajema, Ingeborg M.Leiden University Medical Centre
(author)
The European Vasculitis Society 2016 Meeting Report
- Article/chapterEnglish2017
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LIBRIS-ID:oai:lup.lub.lu.se:8bc8548a-633c-4edb-bd89-f40a961e81cd
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https://lup.lub.lu.se/record/8bc8548a-633c-4edb-bd89-f40a961e81cdURI
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https://doi.org/10.1016/j.ekir.2017.09.008DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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The 2016 European Vasculitis Society (EUVAS) meeting, held in Leiden, the Netherlands, was centered around phenotypic subtyping in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). There were parallel meetings of the EUVAS petals, which here report on disease assessment; database; and long-term follow-up, registries, genetics, histology, biomarker studies, and clinical trials. Studies currently conducted will improve our ability to discriminate between different forms of vasculitis. In a project that involves the 10-year follow-up of AAV patients, we are working on retrieving data on patient and renal survival, relapse rate, the cumulative incidence of malignancies, and comorbidities. Across Europe, several vasculitis registries were developed covering over 10,000 registered patients. In the near future, these registries will facilitate clinical research in AAV on a scale hitherto unknown. Current studies on the genetic background of AAV will explore the potential prognostic significance of genetic markers and further refine genetic associations with distinct disease subsets. The histopathological classification of ANCA-associated glomerulonephritis is currently evaluated in light of data coming out of a large international validation study. In our continuous search for biomarkers to predict clinical outcome, promising new markers are important subjects of current research. Over the last 2 decades, a host of clinical trials have provided evidence for refinement of therapeutic regimens. We give an overview of clinical trials currently under development, and consider refractory vasculitis in detail. The goal of EUVAS is to stimulate ongoing research in clinical, serological, and histological management and techniques for patients with systemic vasculitis, with an outlook on the applicability for clinical trials.
Subject headings and genre
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ANCA
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renal outcome
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therapy
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vasculitis
Added entries (persons, corporate bodies, meetings, titles ...)
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Bruijn, Jan A.Leiden University Medical Centre
(author)
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Casian, AlinaGuy's and St Thomas' NHS Foundation Trust
(author)
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Cid, Maria C.University of Barcelona
(author)
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Csernok, ElenaUniversity Hospital of Tubingen
(author)
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van Daalen, EmmaLeiden University Medical Centre
(author)
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Harper, LorraineUniversity of Birmingham
(author)
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Hauser, ThomasImmunologie-Zentrum Zürich
(author)
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Little, Mark A.Trinity College Dublin
(author)
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Luqmani, Raashid A.University of Oxford
(author)
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Mahr, AlfredCochin Hospital
(author)
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Ponte, CristinaUniversity of Lisbon
(author)
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Salama, AlanUniversity College London
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Segelmark, MårtenLinköping University(Swepub:lu)njur-mse
(author)
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Suzuki, KazuoTeikyo University School of Medicine
(author)
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Sznajd, JanUniversity of Aberdeen
(author)
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Teng, Y. K.OnnoLeiden University Medical Centre
(author)
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Vaglio, AugustoParma University Hospital
(author)
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Westman, KerstinLund University,Lunds universitet,Autoimmunitet och njursjukdomar,Forskargrupper vid Lunds universitet,Autoimmunity and kidney diseases,Lund University Research Groups(Swepub:lu)njur-kwe
(author)
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Jayne, DavidUniversity of Cambridge
(author)
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Leiden University Medical CentreGuy's and St Thomas' NHS Foundation Trust
(creator_code:org_t)
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In:Kidney International Reports: Elsevier BV2:6, s. 1018-10312468-0249
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Bajema, Ingeborg ...
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Bruijn, Jan A.
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Casian, Alina
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Cid, Maria C.
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Csernok, Elena
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van Daalen, Emma
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Harper, Lorraine
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Hauser, Thomas
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Little, Mark A.
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Luqmani, Raashid ...
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Mahr, Alfred
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Ponte, Cristina
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Salama, Alan
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Segelmark, Mårte ...
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Suzuki, Kazuo
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Sznajd, Jan
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Teng, Y. K.Onno
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Vaglio, Augusto
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Westman, Kerstin
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Jayne, David
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