onr:"swepub:oai:lup.lub.lu.se:8c02b38e-6842-43bc-81a7-7a0e9cac998b"
Search: onr:"swepub:oai:lup.lub.lu.se:8c02b38e-6842-43bc-81a7-7a0e9cac998b" > Familial risks for ...
- 1 of 1
- Previous record
- Next record
- To hitlist
Familial risks for childhood acute lymphocytic leukaemia in Sweden and Finland: far exceeding the effects of known germline variants
- Kharazmi, Elham (author)
- da Silva Filho, Miguel I. (author)
- Pukkala, Eero (author)
- show more...
- Thomsen, Hauke (author)
- show less...
- (creator_code:org_t)
- 2012-10-01
- 2012
- English.
- In: British Journal of Haematology. - : Wiley. - 0007-1048. ; 159:5, s. 585-588
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Despite recent successes in the identification of genetic susceptibility loci, no familial risk has been demonstrated for childhood acute lymphoblastic leukaemia (ALL). We identified 3994 childhood ALL cases from two cancer registries; family members were obtained from population registers. The standardized incidence ratio for familial risk in singleton siblings and twins was 3.2 (95% confidence interval 1.55.9) and 162.6 (70.2320.4), respectively. The present data constitute the first demonstration of familial risk for singleton siblings; the high risk for twins is believed to result from shared prenatal blood circulation. The data suggest that currently unidentified genetic loci underlie these observed familial effects.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Keyword
- familial cancer
- standardized incidence ratio
- childhood acute
- lymphocytic leukaemia
- susceptibility genes
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
- British Journal of Haematology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Kharazmi, Elham
- da Silva Filho, ...
- Pukkala, Eero
- Sundquist, Krist ...
- Thomsen, Hauke
- Hemminki, Kari
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Hematology
- Articles in the publication
- British Journal ...
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
