Somatic and anxiety symptoms of depression are associated with disability in late life depression

Objectives: To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression. Method: Data were analyzed from 78 older adults aged 65–88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of these symptoms. Other symptoms of depression were also assessed using the remaining items of the HDRS. Current physical health burden was assessed using the Functional Comorbidity Index (FCI). Disability was measured with the Late Life Function and Disability Instrument (LLFDI) total limitation score. A linear regression analysis was performed to assess the association of somatic and anxiety symptoms with disability independent of other factors. Results: The model accounted for 26.6% of variance in disability, (F(6,51) = 3.1, p =.01). Somatic (B = −1.9, p =.004) and anxiety (B = −3.7, p =.04) symptoms of depression were significantly associated with disability. Other depressive symptoms and physical illness burden were not associated with disability. Discussion: In older adults with major depression, somatic and anxiety symptoms of depression are associated with disability. Identification and treatment to remission of these symptoms may improve functional outcomes among older depressed adults.

Nelson, CraigUniversity of California, San Francisco (author)
Bickford, DavidSan Francisco Veterans Administration Medical Center (author)
Insel, Philip S.Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,San Francisco Veterans Administration Medical Center(Swepub:lu)med-ppi (author)
Mackin, R. ScottSan Francisco Veterans Administration Medical Center (author)
San Francisco Veterans Administration Medical CenterUniversity of California, San Francisco (creator_code:org_t)

In:Aging and Mental Health: Informa UK Limited24:8, s. 1225-12281360-78631364-6915

By the author/editor: Morin, Ruth T.; Nelson, Craig; Bickford, David; Insel, Philip S.; Mackin, R. Scott

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Geriatrics

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