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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03093naa a2200313 4500 | |
| 001 | oai:lup.lub.lu.se:9351764d-c65c-417d-be0c-5ec43504e7d6 | |
| 003 | SwePub | |
| 008 | 190624s1990 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/9351764d-c65c-417d-be0c-5ec43504e7d62 URI |
| 024 | 7 | a https://doi.org/10.3109/003655290091079342 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Barros, H.u Skåne University Hospital4 aut |
| 245 | 1 0 | a Hydrolysis of phosphatidylinositol by human panreatic phospholipase A2 |
| 264 | c 2009-07-08 | |
| 264 | 1 | b Informa UK Limited,c 1990 |
| 520 | a Pure human pancreatic phospholipase A2 efficiently hydrolyzed the 2-ester bond of 14C-2-linoleoyl and 14C-2-arachidonyl phosphatidylinositol (PI). The rate of hydrolysis varied markedly with the bile salt (sodium taurocholate to sodium taurodeoxycholate, 3:4 mol/mol) concentration, the hydrolysis being decreased with increasing bile salt to PI ratio. The influence of bile salts was thus similar to that which has earlier been described for the hydrolysis of phosphatidylcholine (PC) with pig pancreatic phospholipase A2. When 2-3H-arachidonyl PC and 2-14C-arachidonyl PI were incorporated into a mixed substrate, PI was hydrolyzed even faster than PC, the hydrolysis of both phospholipids varying in the same manner with bile salt concentration. 2-14C-arachidonyl PI was also efficiently hydrolyzed by human duodenal content, although at a somewhat slower rate than 2-3H-arachidonyl PC. It is concluded that PI is a good substrate for human phospholipase A2. This minor but arachidonate-rich dietary phospholipid may thus be digested and absorbed by pathways similar to those of the major dietary and bile phospholipid, phosphatidylcholine. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
| 700 | 1 | a Sternby, Beritu Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-bst |
| 700 | 1 | a Nilsson, Åkeu Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Gastro,Forskargrupper vid Lunds universitet,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)med-ani |
| 710 | 2 | a Skåne University Hospitalb Medicin, Lund4 org |
| 773 | 0 | t Scandinavian Journal of Gastroenterologyd : Informa UK Limitedg 25:2, s. 134-140q 25:2<134-140x 1502-7708x 0036-5521 |
| 856 | 4 | u http://dx.doi.org/10.3109/00365529009107934y FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/9351764d-c65c-417d-be0c-5ec43504e7d6 |
| 856 | 4 8 | u https://doi.org/10.3109/00365529009107934 |
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