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Pharmacokinetic and...
Pharmacokinetic and pharmacodynamic variability as possible causes for different drug responses in migraine. A comment
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Tfelt-Hansen, P (author)
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- Edvinsson, Lars (author)
- Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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(creator_code:org_t)
- 2016-06-26
- 2007
- English.
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In: Cephalalgia. - : SAGE Publications. - 0333-1024 .- 1468-2982. ; 27:10, s. 1091-1093
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Abstract
Subject headings
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- The pharmacokinetics of antimigraine drugs zolmitriptan and sumatriptan varied considerably with a fourfold to 10-fold variation in plasma levels. In addition, the pharmacodynamics of triptans as investigated in vitro also varied considerably. In theory, there should probably be a 10-fold variation in doses available, but in clinical practice a fourfold difference in doses will probably cover the needs of most patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Annan klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Other Clinical Medicine (hsv//eng)
Keyword
- pharmacokinetics
- migraine
- variability
- pharmacodynamics
Publication and Content Type
- for (subject category)
- ref (subject category)
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