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Safety, tolerability, and efficacy of TEV-48125 for preventive treatment of chronic migraine: a multicentre, randomised, double-blind, placebo-controlled, phase 2b study.
- Bigal, Marcelo E (author)
-
- Edvinsson, Lars (author)
- Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
- Rapoport, Alan M (author)
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- Lipton, Richard B (author)
- Spierings, Egilius L H (author)
- Diener, Hans-Christoph (author)
- Burstein, Rami (author)
- Loupe, Pippa S (author)
- Ma, Yuju (author)
- Yang, Ronghua (author)
- Silberstein, Stephen D (author)
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- (creator_code:org_t)
- 2015
- 2015
- English.
- In: Lancet Neurology. - 1474-4465. ; 14:11, s. 1091-1100
- Journal article (peer-reviewed)
Abstract
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- Benefits of calcitonin-gene related peptide (CGRP) inhibition have not been established in chronic migraine. Here we assess the safety, tolerability, and efficacy of two doses of TEV-48125, a monoclonal anti-CGRP antibody, in the preventive treatment of chronic migraine.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
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- Burstein, Rami
- Loupe, Pippa S
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