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Longitudinal evalua...
Longitudinal evaluation of cartilage after osteochondral autogenous transfer with delayed gadolinium-enhanced MRI of the cartilage (dGEMRIC)
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Shirai, Takaaki (author)
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Kobayashi, Masahiko (author)
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Nakamura, Shinichiro (author)
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Arai, Ryuzo (author)
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Nishitani, Kohei (author)
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Satake, Tsuyoshi (author)
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- Dahlberg, Leif (author)
- Lund University,Lunds universitet,Enheten för led- och mjukvävnadsforskning,Forskargrupper vid Lunds universitet,Joint and Soft Tissue Unit,Lund University Research Groups
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Kuroki, Hiroshi (author)
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Nakagawa, Yasuaki (author)
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Okada, Tomohisa (author)
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Togashi, Kaori (author)
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Nakamura, Takashi (author)
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(creator_code:org_t)
- 2011-07-29
- 2012
- English.
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In: Journal of Orthopaedic Research. - : Wiley. - 1554-527X .- 0736-0266. ; 30:2, s. 221-225
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http://dx.doi.org/10...
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Abstract
Subject headings
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- The aim was to use repeat delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) to estimate glycosaminoglycan (GAG) content in reparative cartilage after osteochondral autogenous transfer (OAT). The study group comprised 7 knees of 7 patients that were examined three times by dGEMRIC, at 3, 6, and 12 months using a 1.5 Tesla MRI system in both OAT operated and nonoperated condyles at 90 min after the injection. The gadolinium diethylene triamine pentaacetic acid (Gd-DTPA)2- containing contrast medium (0.2 mmols/kg) was injected intravenously. The mean T1 values of the plug cartilage at 3, 6, and 12 months after OAT was 230 +/- 40, 213 +/- 31, and 230 +/- 23 ms (mean +/- SD), respectively. There were differences between the plug and control cartilage at 3 (p<0.01) and 12 (p<0.05) months after OAT, but not at 6 months (p=0.089). No T1 changes were detected between the plug cartilage at the different time points after OAT. The fact that the GAG content of the OAT plugs were maintained for 12-month study period suggest that no major deterioration of load-bearing properties occurs in the cartilage after the OAT. (C) 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 30:221225, 2012
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Keyword
- cartilage
- osteochondral autogenous transfer (OAT)
- dGEMRIC
- MRI
- knee
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Shirai, Takaaki
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Kobayashi, Masah ...
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Nakamura, Shinic ...
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Arai, Ryuzo
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Nishitani, Kohei
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Satake, Tsuyoshi
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show more...
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Dahlberg, Leif
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Kuroki, Hiroshi
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Nakagawa, Yasuak ...
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Okada, Tomohisa
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Togashi, Kaori
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Nakamura, Takash ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Orthopaedics
- Articles in the publication
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Journal of Ortho ...
- By the university
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Lund University