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Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.

Schelbergen, R F (author)
Geven, E J (author)
van den Bosch, M H J (author)
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Eriksson, H (author)
Leanderson, Tomas (author)
Lund University,Lunds universitet,Immunologi,Forskargrupper vid Lunds universitet,Immunology,Lund University Research Groups
Vogl, T (author)
Roth, J (author)
van de Loo, F A J (author)
Koenders, M I (author)
van der Kraan, P M (author)
van den Berg, W B (author)
Blom, A B (author)
van Lent, P L E M (author)
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 (creator_code:org_t)
2015-05-12
2015
English.
In: Annals of the Rheumatic Diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 74:12, s. 2254-2258
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound preventing S100A9 binding to TLR-4. We investigated the effect of paquinimod on experimental OA and human OA synovium.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)

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art (subject category)
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