Search: onr:"swepub:oai:lup.lub.lu.se:9ad9da53-2906-4df4-9713-12500653aacb" >
The Causative Class...
The Causative Classification of Stroke system An international reliability and optimization study
-
Arsava, E. M. (author)
-
Ballabio, E. (author)
-
Benner, T. (author)
-
show more...
-
Cole, J. W. (author)
-
Delgado-Martinez, M. P. (author)
-
Dichgans, M. (author)
-
Fazekas, F. (author)
-
Furie, K. L. (author)
-
Illoh, K. (author)
-
Jood, K. (author)
-
Kittner, S. (author)
-
- Lindgren, Arne (author)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
-
Majersik, J. J. (author)
-
Macleod, M. J. (author)
-
Meurer, W. J. (author)
-
Montaner, J. (author)
-
Olugbodi, A. A. (author)
-
Pasdar, A. (author)
-
Redfors, P. (author)
-
Schmidt, R. (author)
-
Sharma, P. (author)
-
Singhal, A. B. (author)
-
Sorensen, A. G. (author)
-
Sudlow, C. (author)
-
Thijs, V. (author)
-
Worrall, B. B. (author)
-
Rosand, J. (author)
-
Ay, H. (author)
-
show less...
-
(creator_code:org_t)
- 2010
- 2010
- English.
-
In: Neurology. - 1526-632X. ; 75:14, s. 1277-1284
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Background: Valid and reliable ischemic stroke subtype determination is crucial for well-powered multicenter studies. The Causative Classification of Stroke System (CCS, available at http://ccs.mgh.harvard.edu) is a computerized, evidence-based algorithm that provides both causative and phenotypic stroke subtypes in a rule-based manner. We determined whether CCS demonstrates high interrater reliability in order to be useful for international multicenter studies. Methods: Twenty members of the International Stroke Genetics Consortium from 13 centers in 8 countries, who were not involved in the design and development of the CCS, independently assessed the same 50 consecutive patients with acute ischemic stroke through reviews of abstracted case summaries. Agreement among ratings was measured by kappa statistic. Results: The kappa value for causative classification was 0.80 (95% confidence interval [ CI] 0.78-0.81) for the 5-subtype, 0.79 (95% CI 0.77-0.80) for the 8-subtype, and 0.70 (95% CI 0.69-0.71) for the 16-subtype CCS. Correction of a software-related factor that generated ambiguity improved agreement: kappa = 0.81 (95% CI 0.79-0.82) for the 5-subtype, 0.79 (95% CI 0.77-0.80) for the 8-subtype, and 0.79 (95% CI 0.78-0.80) for the 16-subtype CCS. The kappa value for phenotypic classification was 0.79 (95% CI 0.77-0.82) for supra-aortic large artery atherosclerosis, 0.95 (95% CI 0.93-0.98) for cardioembolism, 0.88 (95% CI 0.85-0.91) for small artery occlusion, and 0.79 (0.76-0.82) for other uncommon causes. Conclusions: CCS allows classification of stroke subtypes by multiple investigators with high reliability, supporting its potential for improving stroke classification in multicenter studies and ensuring accurate means of communication among different researchers, institutions, and eras. Neurology (R) 2010;75:1277-1284
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
-
Neurology
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Arsava, E. M.
-
Ballabio, E.
-
Benner, T.
-
Cole, J. W.
-
Delgado-Martinez ...
-
Dichgans, M.
-
show more...
-
Fazekas, F.
-
Furie, K. L.
-
Illoh, K.
-
Jood, K.
-
Kittner, S.
-
Lindgren, Arne
-
Majersik, J. J.
-
Macleod, M. J.
-
Meurer, W. J.
-
Montaner, J.
-
Olugbodi, A. A.
-
Pasdar, A.
-
Redfors, P.
-
Schmidt, R.
-
Sharma, P.
-
Singhal, A. B.
-
Sorensen, A. G.
-
Sudlow, C.
-
Thijs, V.
-
Worrall, B. B.
-
Rosand, J.
-
Ay, H.
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Neurology
- Articles in the publication
-
Neurology
- By the university
-
Lund University