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- Alvarado-kristensson, MariaLund University,Lunds universitet,Molekylär patologi, Malmö,Forskargrupper vid Lunds universitet,Molecular Pathology, Malmö,Lund University Research Groups,Skåne University Hospital (author)
γ-tubulin as a signal-transducing molecule and meshwork with therapeutic potential
- Article/chapterEnglish2018
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- 2018-09-14
- Springer Science and Business Media LLC,2018
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- LIBRIS-ID:oai:lup.lub.lu.se:9af215a9-98d9-4fbd-9c32-c9bd48db26df
- https://lup.lub.lu.se/record/9af215a9-98d9-4fbd-9c32-c9bd48db26dfURI
- https://doi.org/10.1038/s41392-018-0021-xDOI
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- Language:English
- Summary in:English
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- Knowledge of γ-tubulin is increasing with regard to the cellular functions of this protein beyond its participation in microtubule nucleation. γ-Tubulin expression is altered in various malignancies, and changes in the TUBG1 gene have been found in patients suffering from brain malformations. This review recapitulates the known functions of γ-tubulin in cellular homeostasis and discusses the possible influence of the protein on disease development and cancer.
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- Molekylär patologi, MalmöForskargrupper vid Lunds universitet (creator_code:org_t)
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- In:Signal Transduction and Targeted Therapy: Springer Science and Business Media LLC32059-3635
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