onr:"swepub:oai:lup.lub.lu.se:9e89c8d9-5ad0-401e-8a9b-67cc8e55b5f7"
Search: onr:"swepub:oai:lup.lub.lu.se:9e89c8d9-5ad0-401e-8a9b-67cc8e55b5f7" > Synthesis of Fused ...
- 1 of 1
- Previous record
- Next record
- To hitlist
Synthesis of Fused Tertazole- and Imidazole Derivatives via Iodocyclization.
-
- Ek, Fredrik (author)
- Lund University,Lunds universitet,Kemisk biologi med inriktning mot läkemedelsutveckling,Forskargrupper vid Lunds universitet,Chemical Biology and Therapeutics,Lund University Research Groups
- Wistrand, Lars-Göran (author)
-
- Frejd, Torbjörn (author)
- Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
- (creator_code:org_t)
- 2003
- 2003
- English.
- In: Tetrahedron. - 0040-4020. ; 59:35, s. 6759-6769
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The possibility to prepare fused tetrazole- and imidazole derivatives by iodocyclization in moderate to excellent yields is demonstrated. In some examples the cyclizations were not following Baldwin's rules entirely, i.e. exo-selectivity. Nucleophilic substitution of the formed iodides gave different results depending on the hardness of the nucleophile. Thus, elimination of the iodide could be a problem but a substitution reaction with ethyl potassium xanthate and a radical reaction using acrylonitrile were tolerated. In addition, we showed that it is possible to selectively use three iodo substituents individually in one of the fused imidazole derivatives.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Ek, Fredrik
- Wistrand, Lars-G ...
- Frejd, Torbjörn
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Chemical Science ...
- and Organic Chemistr ...
- Articles in the publication
- Tetrahedron
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
