Care of Late-Stage Parkinsonism : Resource Utilization of the Disease in Five European Countries

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Care of Late-Stage Parkinsonism : Resource Utilization of the Disease in Five European Countries

Kruse, Christopher (author): University of Duisburg-Essen

Lipinski, Anna (author): University of Duisburg-Essen,Philipp University of Marburg

Verheyen, Malte (author): University of Duisburg-Essen

Balzer-Geldsetzer, Monika (author): University of Duisburg-Essen,Philipp University of Marburg

Wittenberg, Michael (author): Philipp University of Marburg

Lorenzl, Stefan (author): Paracelsus Private Medical University of Salzburg,University Hospital Munich

Richinger, Carmen (author): Paracelsus Private Medical University of Salzburg

Schmotz, Christian (author): Paracelsus Private Medical University of Salzburg

Tönges, Lars (author): St. Josef-Hospital im Katholischen Klinikum Bochum,Ruhr-University Bochum

Woitalla, Dirk (author): St. Josef-Krankenhaus Kupferdreh

Klebe, Stephan (author): University Hospital Essen

Bloem, Bastiaan R. (author): Radboud University Medical Center

Hommel, Adrianus (author): Radboud University Medical Center

Meissner, Wassilios G. (author): University of Bordeaux

Laurens, Brice (author): University of Bordeaux

Boraud, Thomas (author): University of Bordeaux

Foubert-Samier, Alexandra (author): University of Bordeaux

Vergnet, Sylvain (author): University of Bordeaux

Tison, François (author): University of Bordeaux

Costa, Nadège (author): Toulouse University Hospital

Odin, Per (author): Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Restorative Parkinson Unit,Forskargrupper vid Lunds universitet,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,LU Profile Area: Proactive Ageing,Lund University Profile areas

Rosqvist, Kristina (author): Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Restorative Parkinson Unit,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups

Norlin, Jenny M. (author): IHE – The Swedish Institute for Health Economics

Hjalte, Frida (author): IHE – The Swedish Institute for Health Economics

Schrag, Anette (author): University College London

Dodel, Richard (author): Philipp University of Marburg,University of Duisburg-Essen

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2024
2024
English 14 s.
In: Movement Disorders. - 0885-3185. ; 39:3, s. 571-584

Related links:: http://dx.doi.org/10... (free); show more...; https://lup.lub.lu.s...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Background: Parkinson's disease (PD) is a neurodegenerative disease that leads to progressive disability. Cost studies have mainly explored the early stages of the disease, whereas late-stage patients are underrepresented. Objective: The aim is to evaluate the resource utilization and costs of PD management in people with late-stage disease. Methods: The Care of Late-Stage Parkinsonism (CLaSP) study collected economic data from patients with late-stage PD and their caregivers in five European countries (France, Germany, the Netherlands, UK, Sweden) in a range of different settings. Patients were eligible to be included if they were in Hoehn and Yahr stage >3 in the on state or Schwab and England stage at 50% or less. In total, 592 patients met the inclusion criteria and provided information on their resource utilization. Costs were calculated from a societal perspective for a 3-month period. A least absolute shrinkage and selection operator approach was utilized to identify the most influential independent variables for explaining and predicting costs. Results: During the 3-month period, the costs were €20,573 (France), €19,959 (Germany), €18,319 (the Netherlands), €25,649 (Sweden), and €12,156 (UK). The main contributors across sites were formal care, hospitalization, and informal care. Gender, age, duration of the disease, Unified Parkinson's Disease Rating Scale 2, the EQ-5D-3L, and the Schwab and England Scale were identified as predictors of costs. Conclusion: Costs in this cohort of individuals with late-stage PD were substantially higher compared to previously published data on individuals living in earlier stages of the disease. Resource utilization in the individual sites differed in part considerably among these three parameters mentioned.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)

Keyword

cost-of-illness
late-stage parkinsonism
Parkinson's disease
resource utilization

Publication and Content Type

art (subject category)
ref (subject category)

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