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  • Kruse, ChristopherUniversity of Duisburg-Essen (author)

Care of Late-Stage Parkinsonism : Resource Utilization of the Disease in Five European Countries

  • Article/chapterEnglish2024

Publisher, publication year, extent ...

  • 2024
  • 14 s.

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  • LIBRIS-ID:oai:lup.lub.lu.se:a0f6f66a-6fd2-4688-856a-004b38661849
  • https://lup.lub.lu.se/record/a0f6f66a-6fd2-4688-856a-004b38661849URI
  • https://doi.org/10.1002/mds.29718DOI

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  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

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  • Background: Parkinson's disease (PD) is a neurodegenerative disease that leads to progressive disability. Cost studies have mainly explored the early stages of the disease, whereas late-stage patients are underrepresented. Objective: The aim is to evaluate the resource utilization and costs of PD management in people with late-stage disease. Methods: The Care of Late-Stage Parkinsonism (CLaSP) study collected economic data from patients with late-stage PD and their caregivers in five European countries (France, Germany, the Netherlands, UK, Sweden) in a range of different settings. Patients were eligible to be included if they were in Hoehn and Yahr stage >3 in the on state or Schwab and England stage at 50% or less. In total, 592 patients met the inclusion criteria and provided information on their resource utilization. Costs were calculated from a societal perspective for a 3-month period. A least absolute shrinkage and selection operator approach was utilized to identify the most influential independent variables for explaining and predicting costs. Results: During the 3-month period, the costs were €20,573 (France), €19,959 (Germany), €18,319 (the Netherlands), €25,649 (Sweden), and €12,156 (UK). The main contributors across sites were formal care, hospitalization, and informal care. Gender, age, duration of the disease, Unified Parkinson's Disease Rating Scale 2, the EQ-5D-3L, and the Schwab and England Scale were identified as predictors of costs. Conclusion: Costs in this cohort of individuals with late-stage PD were substantially higher compared to previously published data on individuals living in earlier stages of the disease. Resource utilization in the individual sites differed in part considerably among these three parameters mentioned.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Lipinski, AnnaUniversity of Duisburg-Essen,Philipp University of Marburg (author)
  • Verheyen, MalteUniversity of Duisburg-Essen (author)
  • Balzer-Geldsetzer, MonikaUniversity of Duisburg-Essen,Philipp University of Marburg (author)
  • Wittenberg, MichaelPhilipp University of Marburg (author)
  • Lorenzl, StefanParacelsus Private Medical University of Salzburg,University Hospital Munich (author)
  • Richinger, CarmenParacelsus Private Medical University of Salzburg (author)
  • Schmotz, ChristianParacelsus Private Medical University of Salzburg (author)
  • Tönges, LarsSt. Josef-Hospital im Katholischen Klinikum Bochum,Ruhr-University Bochum (author)
  • Woitalla, DirkSt. Josef-Krankenhaus Kupferdreh (author)
  • Klebe, StephanUniversity Hospital Essen (author)
  • Bloem, Bastiaan R.Radboud University Medical Center (author)
  • Hommel, AdrianusRadboud University Medical Center (author)
  • Meissner, Wassilios G.University of Bordeaux (author)
  • Laurens, BriceUniversity of Bordeaux (author)
  • Boraud, ThomasUniversity of Bordeaux (author)
  • Foubert-Samier, AlexandraUniversity of Bordeaux (author)
  • Vergnet, SylvainUniversity of Bordeaux (author)
  • Tison, FrançoisUniversity of Bordeaux (author)
  • Costa, NadègeToulouse University Hospital (author)
  • Odin, PerLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Restorative Parkinson Unit,Forskargrupper vid Lunds universitet,LU profilområde: Proaktivt åldrande,Lunds universitets profilområden,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,LU Profile Area: Proactive Ageing,Lund University Profile areas(Swepub:lu)med-poi (author)
  • Rosqvist, KristinaLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Restorative Parkinson Unit,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups(Swepub:lu)med-krq (author)
  • Norlin, Jenny M.IHE – The Swedish Institute for Health Economics (author)
  • Hjalte, FridaIHE – The Swedish Institute for Health Economics (author)
  • Schrag, AnetteUniversity College London (author)
  • Dodel, RichardUniversity of Duisburg-Essen,Philipp University of Marburg (author)
  • University of Duisburg-EssenPhilipp University of Marburg (creator_code:org_t)

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