Peptide-Oleate Complexes Create Novel Membrane-Bound Compartments

Hansen, Jesper S. (author): Lund University,Lunds universitet,Medicinsk strukturbiologi,Forskargrupper vid Lunds universitet,Medical Structural Biology,Lund University Research Groups

Tran, Tuan Hiep (author): Lund University,Lunds universitet,Cancerinfektion,Forskargrupper vid Lunds universitet,Cancer Infection,Lund University Research Groups

Cavalera, Michele (author): Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine

Paul, Sanchari (author): Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine

Chaudhuri, Arunima (author): Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine

Lindkvist-Petersson, Karin (author): Lund University,Lunds universitet,Medicinsk strukturbiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Medical Structural Biology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments

Ho, James C.S. (author): Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine,Nanyang Technological University

Svanborg, Catharina (author): Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments

(creator_code:org_t)

2020-06-10
2020
English 11 s.
In: Molecular biology and evolution. - : Oxford University Press (OUP). - 0737-4038 .- 1537-1719. ; 37:11, s. 3083-3093

Related links:: http://dx.doi.org/10... (free); show more...; https://academic.oup...; https://lup.lub.lu.s...; https://doi.org/10.1...; show less...

Abstract Subject headings

A challenging question in evolutionary theory is the origin of cell division and plausible molecular mechanisms involved. Here, we made the surprising observation that complexes formed by short alpha-helical peptides and oleic acid can create multiple membrane-enclosed spaces from a single lipid vesicle. The findings suggest that such complexes may contain the molecular information necessary to initiate and sustain this process. Based on these observations, we propose a new molecular model to understand protocell division.

By the author/editor: Hansen, Jesper S ...; Tran, Tuan Hiep; Cavalera, Michel ...; Paul, Sanchari; Chaudhuri, Aruni ...; Lindkvist-Peters ...; show more...; Ho, James C.S.; Svanborg, Cathar ...; show less...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Biological Scien ...; and Biochemistry and ...

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