Sorting of Breast Cancer Cell into Different Subpopulations towards Long-Term Observation

Yilmaz, Esra (author): Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Other operations, LTH,Faculty of Engineering, LTH,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

Beech, Jason P. (author): Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Other operations, LTH,Faculty of Engineering, LTH,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH

Tegenfeldt, Jonas O. (author): Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Other operations, LTH,Faculty of Engineering, LTH,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH,LUCC: Lund University Cancer Centre,Other Strong Research Environments

(creator_code:org_t)

2022
2022
English 2 s.
In: MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - 9781733419048 ; , s. 322-323

Abstract Subject headings

To study how mechanical factors influence the spread of cancer and the surrounding extracellular matrix (ECM), it is crucial that cancer cell populations be sorted without labels in relevant subpopulations with respect to mechanical properties. It is also important to confine subpopulations for long-term observation to track changes, in inherent properties of the subpopulations, and on the influence of the sorting. We have used Deterministic Lateral Displacement (DLD) for label-free continuous sorting of breast cancer cells into three different subpopulations. These were subsequently cultured for further analyses of their differences and to observe any alterations due to the sorting.

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Biological Scien ...; and Biophysics

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