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  • Britton, Annie RUniversity College London (author)

Alcohol consumption and common carotid intima-media thickness : The USE-IMT study

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2017-05-19
  • Oxford University Press (OUP),2017
  • 4 s.

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:a4d63fdd-4115-4f15-ae0d-a0fda4f2a36f
  • https://lup.lub.lu.se/record/a4d63fdd-4115-4f15-ae0d-a0fda4f2a36fURI
  • https://doi.org/10.1093/alcalc/agx028DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Aims: Epidemiological evidence indicates a protective effect of light to moderate alcohol consumption compared to non-drinking and heavy drinking. Although several mechanisms have been suggested, the effect of alcohol on atherosclerotic changes in vessel walls is unclear. Therefore, we explored the relationship between alcohol consumption and common carotid intima media thickness, a marker of early atherosclerosis in the general population. Methods: Individual participant data from eight cohorts, involving 37,494 individuals from the USE-IMT collaboration were used. Multilevel age and sex adjusted linear regression models were applied to estimate mean differences in common carotid intima-media thickness (CIMT) with alcohol consumption. Results: The mean age was 57.9 years (SD 8.6) and the mean CIMT was 0.75 mm (SD 0.177). About, 40.5% reported no alcohol consumed, and among those who drank, mean consumption was 13.3 g per day (SD 16.4). Those consuming no alcohol or a very small amount (<5 g per day) had significantly lower common CIMT values than those consuming >10 g per day, after adjusting for a range of confounding factors. Conclusion: In this large CIMT consortium, we did not find evidence to support a protective effect of alcohol on CIMT.

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  • Grobbee, Diederick E.University Medical Center Utrecht (author)
  • Den Ruijter, Hester M.University of Calgary (author)
  • Anderson, Todd JColumbia University (author)
  • Desvarieux, MoiseLund University (author)
  • Engström, GunnarLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups(Swepub:lu)smi-gen (author)
  • Evans, Greg WUniversity of Eastern Finland (author)
  • Hedblad, BoLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups(Swepub:lu)medf-bhe (author)
  • Kauhanen, JussiMcMaster University (author)
  • Kurl, SudhirMcMaster University (author)
  • Lonn, Eva MUiT The Arctic University of Norway, Tromsø (author)
  • Mathiesen, Ellisiv BUniversity Medical Center Utrecht (author)
  • Polak, Joseph FTufts University School of Medicine (author)
  • Price, Jacqueline F.University of Edinburgh (author)
  • Rembold, Christopher MUniversity of Virginia (author)
  • Rosvall, MariaLund University,Lunds universitet,Centrum för ekonomisk demografi,Ekonomihögskolan,Socialmedicin och hälsopolitik,Forskargrupper vid Lunds universitet,Centre for Economic Demography,Lund University School of Economics and Management, LUSEM,Social Medicine and Health Policy,Lund University Research Groups(Swepub:lu)smi-mro (author)
  • Rundek, TatjanaUniversity of Miami (author)
  • Salonen, Jukka T.MAS-Metabolic Analytical Services Oy (author)
  • Stehouwer, Coen D AYukioka Hospital (author)
  • Tuomainen, Tomi-PekkaMcMaster University (author)
  • Bots, Michiel L.University Medical Center Utrecht (author)
  • University College LondonUniversity Medical Center Utrecht (creator_code:org_t)

Related titles

  • In:Alcohol and Alcoholism: Oxford University Press (OUP)52:4, s. 483-4860735-04141464-3502

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