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Patient-Oriented Ec...
Patient-Oriented Eczema Measure (POEM), a core instrument to measure symptoms in clinical trials : A Harmonising Outcome Measures for Eczema (HOME) statement
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- Spuls, P. I. (author)
- Academic Medical Center of University of Amsterdam (AMC)
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- Gerbens, L. A A (author)
- Academic Medical Center of University of Amsterdam (AMC)
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- Simpson, E. (author)
- Oregon Health & Science University
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- Apfelbacher, C. J. (author)
- University of Regensburg
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- Chalmers, J. R. (author)
- University of Nottingham
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- Thomas, K. S. (author)
- University of Nottingham
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- Prinsen, C. A C (author)
- Amsterdam UMC - Vrije Universiteit Amsterdam
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- von Kobyletzki, L. B. (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups
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- Singh, J. A. (author)
- University of Alabama
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- Williams, H C (author)
- University of Nottingham
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- Schmitt, J. (author)
- University Clinic Carl Gustav Carus at the TU Dresden
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(creator_code:org_t)
- 2017-03-02
- 2017
- English.
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In: British Journal of Dermatology. - : Oxford University Press (OUP). - 0007-0963. ; 176:4, s. 979-984
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http://dx.doi.org/10...
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Abstract
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- Background: The Harmonising Outcome Measures for Eczema (HOME) initiative has defined four core outcome domains for a core outcome set (COS) to be measured in all atopic eczema (AE) trials to ensure cross-trial comparison: clinical signs, symptoms, quality of life and long-term control. Objectives: The aim of this paper is to report on the consensus process that was used to select the core instrument to consistently assess symptoms in all future AE trials. Methods: Following the HOME roadmap, two systematic reviews were performed which identified three instruments that had sufficient evidence of validity, reliability and feasibility to be considered for the final COS. Results: At the fourth international HOME meeting, there was broad consensus among all stakeholders that the Patient-Oriented Eczema Measure (POEM) should be used as the core instrument (87·5% agreed, 9·4% unsure, 3·1% disagreed). Conclusions: All relevant stakeholders are encouraged to use POEM as the chosen instrument to measure the core domain of symptoms in all future AE clinical trials. Other instruments of interest can be used in addition to POEM.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Övrig annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Other Medical and Health Sciences not elsewhere specified (hsv//eng)
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- art (subject category)
- ref (subject category)
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- By the author/editor
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Spuls, P. I.
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Gerbens, L. A A
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Simpson, E.
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Apfelbacher, C. ...
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Chalmers, J. R.
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Thomas, K. S.
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show more...
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Prinsen, C. A C
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von Kobyletzki, ...
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Singh, J. A.
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Williams, H C
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Schmitt, J.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Other Medical an ...
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and Other Medical an ...
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British Journal ...
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Lund University