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Daily intake of mil...
Daily intake of milk powder and risk of celiac disease in early childhood : A nested case-control study
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- Hård af Segerstad, Elin M. (author)
- Lund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups
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- Lee, Hye Seung (author)
- University of South Florida
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- Aronsson, Carin Andrén (author)
- Lund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups
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- Yang, Jimin (author)
- University of South Florida
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- Uusitalo, Ulla (author)
- University of South Florida
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- Sjöholm, Ingegerd (author)
- Lund University,Lunds universitet,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH
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- Rayner, Marilyn (author)
- Lund University,Lunds universitet,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH
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- Kurppa, Kalle (author)
- University of Tampere,Tampere University Hospital
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- Virtanen, Suvi M. (author)
- Tampere University Hospital,Finnish National Institute for Health and Welfare,University of Tampere
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- Norris, Jill M. (author)
- University of Colorado
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- Agardh, Daniel (author)
- Lund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups
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(creator_code:org_t)
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- 2018-04-28
- 2018
- English.
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In: Nutrients. - : MDPI AG. - 2072-6643. ; 10:5
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Abstract
Subject headings
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- Milk powder and gluten are common components in Swedish infants’ diets. Whereas large intakes of gluten early in life increases the risk of celiac disease in genetically at-risk Swedish children, no study has yet evaluated if intake of milk powder by 2 years of age is associated with celiac disease. A 1-to-3 nested case-control study, comprised of 207 celiac disease children and 621 controls matched for sex, birth year, and HLA genotype, was performed on a birth cohort of HLA-DR3-DQ2 and/or DR4-DQ8-positive children. Subjects were screened annually for celiac disease using tissue transglutaminase autoantibodies (tTGA). Three-day food records estimated the mean intake of milk powder at ages 6 months, 9 months, 12 months, 18 months, and 24 months. Conditional logistic regression calculated odds ratios (OR) at last intake prior to seroconversion of tTGA positivity, and for each time-point respectively and adjusted for having a first-degree relative with celiac disease and gluten intake. Intake of milk powder prior to seroconversion of tTGA positivity was not associated with celiac disease (OR = 1.00; 95% CI = 0.99, 1.03; p = 0.763). In conclusion, intake of milk powder in early childhood is not associated with celiac disease in genetically susceptible children.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- Commercial infant foods
- Formula
- Gluten
- HLA
- Infant feeding
- Milk powder
- Sweden
Publication and Content Type
- art (subject category)
- ref (subject category)
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Nutrients
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Hård af Segersta ...
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Lee, Hye Seung
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Aronsson, Carin ...
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Yang, Jimin
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Uusitalo, Ulla
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Sjöholm, Ingeger ...
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Rayner, Marilyn
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Kurppa, Kalle
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Virtanen, Suvi M ...
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Norris, Jill M.
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Agardh, Daniel
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- MEDICAL AND HEALTH SCIENCES
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Nutrients
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Lund University