SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:lup.lub.lu.se:afe4e497-d06a-4cdf-b921-9ee163a47245"
 

Search: onr:"swepub:oai:lup.lub.lu.se:afe4e497-d06a-4cdf-b921-9ee163a47245" > Controlled assembly...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Controlled assembly of retinal cells on fractal and Euclidean electrodes

Moslehi, Saba (author)
University of Oregon
Rowland, Conor (author)
University of Oregon
Smith, Julian H. (author)
University of Oregon
show more...
Watterson, William J. (author)
University of Oregon
Miller, David (author)
University of Oregon
Niell, Cristopher M. (author)
University of Oregon
Alemán, Benjamín J. (author)
University of Oregon
Perez, Maria Thereza (author)
Lund University,Lunds universitet,NanoLund: Centre for Nanoscience,Annan verksamhet, LTH,Lunds Tekniska Högskola,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nanomaterial för retinala implantat,Forskargrupper vid Lunds universitet,Other operations, LTH,Faculty of Engineering, LTH,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Nanomaterials for retinal prostheses,Lund University Research Groups
Taylor, Richard P. (author)
University of Oregon
show less...
 (creator_code:org_t)
2022-04-06
2022
English.
In: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 17:4
Related links:
http://dx.doi.org/10... (free)
show more...
https://lup.lub.lu.s...
https://doi.org/10.1...
show less...
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Controlled assembly of retinal cells on artificial surfaces is important for fundamental cell research and medical applications. We investigate fractal electrodes with branches of vertically- aligned carbon nanotubes and silicon dioxide gaps between the branches that form repeating patterns spanning from micro- to milli-meters, along with single-scaled Euclidean electrodes. Fluorescence and electron microscopy show neurons adhere in large numbers to branches while glial cells cover the gaps. This ensures neurons will be close to the electrodes' stimulating electric fields in applications. Furthermore, glia won't hinder neuronbranch interactions but will be sufficiently close for neurons to benefit from the glia's life-supporting functions. This cell 'herding' is adjusted using the fractal electrode's dimension and number of repeating levels. We explain how this tuning facilitates substantial glial coverage in the gaps which fuels neural networks with small-world structural characteristics. The large branch-gap interface then allows these networks to connect to the neuron-rich branches.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Oftalmologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Ophthalmology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)

Publication and Content Type

art (subject category)
ref (subject category)

Find in a library

  • PLoS ONE (Search for host publication in LIBRIS)

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view