Search: onr:"swepub:oai:lup.lub.lu.se:b49113d5-716a-415f-9620-4e70dcfcb9be" >
Ancestral susceptib...
Ancestral susceptibility to colorectal cancer
- Article/chapterEnglish2012
Publisher, publication year, extent ...
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2012-01-30
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Oxford University Press (OUP),2012
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LIBRIS-ID:oai:lup.lub.lu.se:b49113d5-716a-415f-9620-4e70dcfcb9be
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https://lup.lub.lu.se/record/2409774URI
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https://doi.org/10.1093/mutage/ger061DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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Every year, approximately 1 million new colorectal cancer (CRC) cases are diagnosed and about half a million people worldwide die due to this cancer. Known differences in CRC incidence rates are mainly attributed to differences in diet and other environmental factors represented, among others, by nutrition-related complex diseases (e.g. obesity and diabetes mellitus type II). Within the last years, it has become evident that environmental risk factors can be complemented by a genetic component when considering the risk of CRC. For example, a number of polymorphisms are known to be associated with an increased risk of obesity and obesity is a risk factor for CRC. Several studies have shown that the 'ancestral-susceptibility model' can be reasonably applied to nutrition-related complex diseases such as obesity. The work in hand shortly discusses whether the ancestral-susceptibility model can also be applied to CRC as a nutrition-related complex disease.
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Pardini, Barbara
(author)
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Naccarati, Alessio
(author)
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Vodicka, Pavel
(author)
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Hemminki, KariLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-khk
(author)
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Försti, AstaLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups(Swepub:lu)med-asf
(author)
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Allmänmedicin och klinisk epidemiologiForskargrupper vid Lunds universitet
(creator_code:org_t)
Related titles
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In:Mutagenesis: Oxford University Press (OUP)27:2, s. 197-2040267-83571464-3804
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