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- Hallberg, ALund University,Skåne University Hospital (author)
Natural killer cell activity and antibody-dependent cellular cytotoxicity in newborn infants
- Article/chapterEnglish1982
Publisher, publication year, extent ...
- Wiley,1982
Numbers
- LIBRIS-ID:oai:lup.lub.lu.se:bb7c62b5-ba32-42dd-b587-9cf7fa24f113
- https://lup.lub.lu.se/record/bb7c62b5-ba32-42dd-b587-9cf7fa24f113URI
- https://doi.org/10.1111/j.1651-2227.1982.tb09447.xDOI
Supplementary language notes
- Language:English
- Summary in:English
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Notes
- The ability of lymphocytes from the peripheral blood of preterm and term infants and adult women and men to mediate natural killing (NK) and K cell activity (antibody-dependent cellular cytotoxicity) was analysed in 4 hours 51Cr-release assays. K 562 cells were targets for NK activity. K cell activity was assayed on antibody-coated rat thymocytes. Lymphocytes from adult male donors were significantly more cytotoxic to K 562 cells than were lymphocytes from adult female donors. Lymphocytes from both preterm and term infants had significantly lower NK and K cell activity than lymphocytes from adult donors. During the first month of life no increase in NK activity or K cell activity occurred in 7 infants who were re-examined. It is concluded that neither NK nor K cell activities are fully developed during the first month of life.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Immunologi inom det medicinska området hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Immunology in the medical area hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
- Adult
- Antibody-Dependent Cell Cytotoxicity
- Cytotoxicity, Immunologic
- Female
- Humans
- Infant
- Infant, Newborn
- Infant, Premature
- Killer Cells, Natural/immunology
- Lymphocytes/immunology
- Male
Added entries (persons, corporate bodies, meetings, titles ...)
- Malmström, PLund University,Lunds universitet,Wallenberglaboratoriet, Lund,Medicinska fakulteten,The Wallenberg Laboratory,Faculty of Medicine,Skåne University Hospital(Swepub:lu)onk-pma (author)
- Lund UniversitySkåne University Hospital (creator_code:org_t)
Related titles
- In:Acta Paediatrica Scandinavica: Wiley71:3, s. 431-4360001-656X0803-52531651-2227
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