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Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
- Mega, Jessica L (author)
- Stitziel, Nathan O (author)
-
- Smith, Gustav (author)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Cardiovascular Research - Hypertension,Lund University Research Groups
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- Chasman, Daniel I (author)
- Caulfield, Mark J (author)
- Devlin, James J (author)
- Nordio, Francesco (author)
- Hyde, Craig L (author)
- Cannon, Christopher P (author)
- Sacks, Frank M (author)
- Poulter, Neil R (author)
- Sever, Peter S (author)
- Ridker, Paul M (author)
- Braunwald, Eugene (author)
- Kathiresan, Sekar (author)
- Sabatine, Marc S (author)
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- (creator_code:org_t)
- 2015
- 2015
- English.
- In: The Lancet. - 1474-547X. ; 385:9984, s. 2264-2271
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Genetic variants have been associated with the risk of coronary heart disease. In this study, we tested whether or not a composite of these variants could ascertain the risk of both incident and recurrent coronary heart disease events and identify those individuals who derive greater clinical benefit from statin therapy.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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- Hyde, Craig L
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- Sacks, Frank M
- Poulter, Neil R
- Sever, Peter S
- Ridker, Paul M
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- Melander, Olle
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- Sabatine, Marc S
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- MEDICAL AND HEALTH SCIENCES
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